Abstract:Background Necrotising enterocolitis (NEC) is the commonest gastrointestinal emergency among premature infants, and accounts for significant morbidity and mortality. Breast milk (BM) is considered as the best nutritional option to prevent NEC. Traditionally cow's milk-based fortifier is added to BM to optimise growth of extremely premature infants, thus potentially increasing the risk of NEC. More recently the value of replacing the traditional cow's milk-based fortifier with human breast milk-based fortifier … Show more
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