Abstract:The circadian clock is a molecular mechanism that synchronizes environment variations with physiological changes. Disruption of the circadian clock has been linked to increased risk in diseases and a number of disorders (e.g. jet lag, insomnia, coronary heart disease and cancer). Period 2 (PER2), a circadian protein, is at the center of the clock's function. The complete loss of per2 has been shown to be common in several types of cancer including breast and ovarian. Epidemiological studies established a corre… Show more
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