“…20 Importantly, p47 phox possesses an actin-binding site, which is 1 of the strongest indicators that this protein interacts with actin/cytoskeletal proteins. 21,22 Numerous protein kinases have been implicated in the phosphorylation of p47 phox , including protein kinase C, Akt, extracellular signal-regulated kinase 1/2, Src, and p21-activated kinase. [23][24][25] Some kinases, such as protein kinase A and casein kinase II, influence p47 phox through a negative inhibitory effect.…”