P4‐327: Montreal Cognitive Assessment (MoCA) population‐based study of Russian elderly

Makeeva, O. A.; Markova, Valentina V.; Жукова, И. А.; Melikyan, Zarui A.; Minaycheva, L. I.; Буйкин, С. В.; Osinova, Elena; Abushaeva, Marina; Botkina, Olga; Мусина, Н. Ф.; Starinskaya, Elena; Жукова, Н. Г.; Maruyama, Yuka; McCart, Michelle; MacDonald, Heather; Whitley, Lawrence; Romero, Heather; Hayden, Kathleen M.; Plassman, Brenda L.; Welsh‐Bohmer, Kathleen A.

doi:10.1016/j.jalz.2013.08.108

Cited by 3 publications

(4 citation statements)

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“…All participants were given the Russian version of MoCA (Makeeva et al, 2012), the LNB (Luria, 1966), and Star Cancellation Test (SCT; Friedman, 1992) together with the Rus-OCS Version A. Normative data were taken from official websites for MoCA and SCT although we note that neither website provided language or cultural specific norms for the Russian population and all used norms were derived from English speakers with translations. The SCT was adapted for the Russian population by replacing English letters and words with the same length Russian stimuli (see Figure 1), according to recommendations from the official SCT website which states the following: "the words can be translated into the patients' native language" (see https://www.strokengine.ca/quick/ sct_quick/).…”

Section: Methodsmentioning

confidence: 99%

“…It has been reported that Russian clinicians use cognitive screens that were developed in other linguistic and cultural settings without adaptation, validation and standardization for Russian speakers (Rasskazova, Kovyazina, & Varako, 2016). For example, Russian versions of the MoCA (Makeeva et al, 2012) and MMSE (Levin et al, 2015) are available. However, there are no normative or standardized guidelines published for use with the Russian clinical population.…”

Section: Cognitive Screening Assessment In Russiamentioning

confidence: 99%

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The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors.

et al. 2019

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The Oxford Cognitive Screen (OCS) is a screening tool for the assessment of poststroke deficits in attention, memory, praxis, language, and number processing. The goal of the present study was to develop a Russian version of the OCS (Rus-OCS) via translation of the original battery, its cultural and linguistic adaptations, and reporting preliminary findings on its psychometric properties. Method: All parts of OCS were translated by native Russian-speaking neuropsychologists. Russian-speaking stroke patients (N ϭ 205) were assessed with the Rus-OCS. Their performance was compared with performance of 60 healthy Russian-speaking adults aged between the ages of 18 and 91 years. The performance of 15 stroke patients and 42 healthy adults were assessed with a parallel version within 7 days of first testing. Convergent validity of the Rus-OCS was established via correlations with comparable tasks. Performance of three stroke groups with different lesion lateralization (right, left, and bilateral) was compared on language and visual attention subtasks. Preliminary normative data based on 5th to 95th percentile were also reported. Results: Measures of internal consistency and test-retest reliability ranged from acceptable to very good and estimates of convergent validity ranged from moderate to high. Sensitivity and specificity was found to range from .56 to 1 and from .73 to 1, respectively. Significant differences in performance between stroke and healthy groups on all subtasks confirmed the discriminative power of the Rus-OCS was good. Conclusions: Rus-OCS is a promising cognitive screening instrument for Russian-speaking patients. However, further validation is needed. Constraints of socioeconomic differences between Russian speakers in the wider population should be considered.

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Section: Methodsmentioning

confidence: 99%

Section: Cognitive Screening Assessment In Russiamentioning

confidence: 99%

The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors.

et al. 2019

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“…В работе было использовано 2 выборки из популяции Томска. Контрольная выборка состояла из 586 пожилых, средний возраст которых составил 70,9±5,7 года, собранных в ходе когортного исследования по первичной профилактике БА [18][19][20] без диагноза БА. В основную выборку вошли 100 больных БА с поздним началом, средний возраст -72,1±7,8 года.…”

Section: материал и методыunclassified

A rare variant in the sortilin-related receptor 1 gene is associated with declined cognitive functions in the elderly

Stepanov

Бочарова

Вагайцева

et al. 2018

Z. nevrol. psikhiatr. im. S.S. Korsakova

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“…Èññëåäîâàíèå âûïîëíåíî íà ãðóïïå èç 695 ïîaeèëûõ ëþäåé (177 ìóae÷èí è 518 aeåíùèí), ó êîòîðûõ ïðîâåäåíà îöåíêà êîãíèòèâíîãî ñòàòóñà ñ ïîìîùüþ áàòàðåè òåñòîâ MoCA [18]. Äàííûå î âûáîðêå ñâåäåíû â òàáë.…”

Section: ìàòåðèàëû è ìåòîäûunclassified

Association of apolipoprotein E gene polymorphism with cognitive abilities variability of elderly people

Марусин¹,

Makeeva²,

Вагайцева³

et al. 2018

Nauchno-Prakticheskii Zhurnal «Medicinskaia Genetika»

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Physiological changes in the brain with natural aging and the development of dementia have a common genetic basis, which makes it important to search for genetic variants that delineate the natural decline in cognitive abilities with age and dementia of the Alzheimer’s type. Objective: the search for the relationship between two polymorphic variants (rs429358 and rs7412) APOE gene and their protein isoforms (apoE) with the variability of cognitive functions in the elderly, determined by Montreal Cognitive Assessmnet (MoCA) total score. The study was performed on a group of 695 elderly people (177 men and 518 women) tested by a battery of MoCA tests. Genotyping was carried out by real-time PCR using TaqMan probes. The analysis of genotypic variability associations with the nominal trait was performed by the Kruskel-Wallis and the median test nonparametric methods.It was shown that the rs429358*C allele carriers and protein isoforms e4/e4+e2/e4+e3/e4 carriers in comparison with the e3/e3 homozygous have the greatest risk of decreased cognitive abilities in old age (OR (95% CI) was 1.51 (1.09 - 2.10), c = 6.66, p = 0.01 and OR = 1.64, 95% CI (1.11 - 2.44), c = 6.76, p = 0.009, respectively). Probably, the revealed associations indicate to the presence of common genes and mechanisms for dementia and intellect with normal variability of cognitive functions inheritance.

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P4‐327: Montreal Cognitive Assessment (MoCA) population‐based study of Russian elderly

Cited by 3 publications

References 0 publications

The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors.

The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors.

A rare variant in the sortilin-related receptor 1 gene is associated with declined cognitive functions in the elderly

Association of apolipoprotein E gene polymorphism with cognitive abilities variability of elderly people

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