P319 Randomized controlled trial of 1% and 5% 5-fluorouracil compared to 90% trichloroacetic acid for anogenital wart treatment

Anggraini, Ika; Hoemardani, Aida S.D.; Nilasari, Hanny; Indriatmi, Wresti

doi:10.1136/sextrans-2019-sti.430

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-Fluorouracil (2a)1

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2024

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“…It is not licensed for the treatment of AGW but has been shown to be effective in various preparations in clinical trials with similar clearance rates to approved topical agents. 23,[70][71][72][73][74][75] In the UK it is available as a 5% cream preparation which is applied thinly once or twice daily for 3-4 weeks. Treatment response is characterised by inflammation and erosion followed by re-epithelialisation.…”

Section: -Fluorouracil (2a)mentioning

confidence: 99%

British association for sexual health and HIV national guideline for the management of anogenital warts in adults (2024)

Nugent,

Apoola,

Coleman

et al. 2024

Int J STD AIDS

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This guideline offers recommendations on the diagnosis, treatment and health promotion principles needed for the effective management of human papillomavirus (HPV)-related warts at anogenital sites including the external genitals, vagina, cervix, urethra, perianus and anal canal. The guideline is aimed primarily at patients aged 16 years or older presenting to healthcare professionals working in level 3 sexual health services in the United Kingdom. However, the principles of the recommendations may be applied in other care settings, including in primary care, using locally adapted care pathways where appropriate. The management of HPV-related anogenital dysplasia or warts at other extragenital sites is outside the scope of this guideline.

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