P31 Genetic Profile in NSLC Biopsy Samples - A Multicenter Local Study

Abstract

both with stage IV pathologies. The entire study population was evaluated for PDL-1 before starting treatment, by IHC. Results: We included 58 patients, 33 patients (57%) had lung cancer and 25 (43%) had other types of tumors. When analyzing the toxicities of both groups it was observed that, the patients with lung cancer showed: Asthenia 20 patients (44%), Skin Rash 8 patients (18%), Diarrhea 3 patients (7%), hypothyroidism 2 patients (5%), liver toxicity 6 patients (13%) and hematological toxicity 6 patients (13%). In the second group patients exhibited: Asthenia 17 patients (61%), Skin Rash 4 patients (14%), Diarrhea 2 patients (7%), hypothyroidism 2 patients (7%) and hematological toxicity 3 patients (11%). Conclusion: In this work, we can observe that in both groups there were expected toxicities. The most frequent one was asthenia, but the group with lung cancer showed greater hepatic and hematological toxicity with a significant difference compared to other tumors.