P300 Event-Related Potentials Differentiate Better Performing Individuals With Traumatic Brain Injury: A Preliminary Study of Semantic Processing

Davis, Tara; Hill, Benjamin D.; Evans, Karen; Tiffin, Shelby; Stanley, Nicholas; Fields, K; Russ, K; Bindele, Huybrechts F.; Gordon-Hickey, Susan

doi:10.1097/htr.0000000000000264

Cited by 9 publications

(7 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Advanced P300 activity was found at the frontal electrode of participants while working memory was being used, unlike younger individuals, in whom greater posterior activation was found. Another study of individuals with posttraumatic brain injury28 found that worse performance on neuropsychological tests was associated with decreased P300 amplitude relative to controls, although a typical P300 parietal wave response was evident. On the other hand, participants who performed better on the neuropsychological tests had robust amplitude for the P300, characterized by the recruitment of anterior brain regions, in addition to parietal activation.…”

Section: Discussionmentioning

confidence: 98%

“…Researchers28 hold that P300 may be a sensitive marker of neural plasticity that could be used to improve functional results in paradigms of cognitive remediation. In view of the correlations reported here, we assume that stimulation of cognition in the practice setting, especially attention and working memory, may result in improved verbal fluency and language among elderly individuals.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Relationship between cognitive processing, language and verbal fluency among elderly individuals

Francisco

Brígola

Ottaviani

et al. 2019

Dement. neuropsychol.

View full text Add to dashboard Cite

Some cognitive dimensions, such as attention, memory and executive functions, may decline with age, while other functions remain intact or even improve due to greater life experience. Objective: to analyze the relationship between cognitive processing, language and verbal fluency among elderly individuals seen by primary healthcare services located in a city in the interior of São Paulo, Brazil. Methods: a cross-sectional study with a quantitative method was conducted. A total of 149 elderly individuals were assessed through previously scheduled interviews. Data collection included a questionnaire on sociodemographic data and the Addenbrooke's Cognitive Examination - Revised (ACE-R). Cognitive processing (P300) was assessed using a device that captures potentials elicited in auditory tasks. Descriptive analysis and Spearman's correlation were performed with the level of significance established at 5%. Results: a negative correlation was found between language and P300 latency, while a positive correlation was found between verbal fluency and P300 amplitude. Comprehension and naming tasks showed a negative correlation with latency. The repetition task revealed a positive correlation with P300 amplitude. Conclusion: although more extensive testing is needed, these findings suggest that language correlates with P300 latency, whereas verbal fluency correlates with P300 amplitude.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Relationship between cognitive processing, language and verbal fluency among elderly individuals

Francisco

Brígola

Ottaviani

et al. 2019

Dement. neuropsychol.

View full text Add to dashboard Cite

show abstract

“…Event-related potentials (P300) is an objective index to reflect the severity and the prognosis judgment of patients with cognitive impairment [ 17 , 18 ]. In the present study, we noted that, before treatment, there were no significant differences in the latency and amplitude of P300 among three groups ( P > 0.05).…”

Section: Resultsmentioning

confidence: 99%

Efficacy of Combined XingZhi‐YiNao Granules and Hyperbaric Oxygen Therapy for Cognition and Motor Dysfunction in Patients with Delayed Encephalopathy after Acute Carbon Monoxide Poisoning

Meihua

Guo

et al. 2017

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Purpose To investigate the efficacy of XingZhi-YiNao (XZYN) granules and hyperbaric oxygenation (HBO) for cognition and motor dysfunction in patients with delayed encephalopathy after acute carbon monoxide poisoning (DEACMP). Methods Eighty-nine patients with DEACMP were randomly divided into control group (n = 19), HBO group (n = 32), and XZYN group (n = 38). All patients received conventional treatment. HBO group received HBO therapy once daily. XZYN group received extra XZYN granules plus HBO treatment. The related indexes including activity of daily living (ADL) scale, Montreal cognitive assessment (MoCA) scale, and mini mental state examination (MMSE) scale were measured. Cerebral white matter injury, age related white matter changes (ARWMC) scale, and the amplitude and latency of P300 were assessed. Results Compared with control group, the neurological function scores of ADL, MoCA, and MMSE in HBO and XZYN groups were significantly improved, the impairment degree of brain white matter and cognition function were obviously alleviated, the latencies of P300 were significantly shortened, and the amplitudes of P300 were evidently increased (P < 0.05). Treatment efficacy of XZYN group was superior to that of HBO group (P < 0.05). Conclusion Combined XZYN granules and HBO can significantly improve cognition and motor functions in patients with DEACMP.

show abstract

mentioning

confidence: 99%

“…2 Low P300 amplitude for speech stimuli correlated with worse recovery prognosis in coma patients after severe brain injury. 15 Several studies showed a correlation of mismatch negativity (MMN) and P300 prominence with consciousness recovery in coma patients. 6 A paradigm that includes event-related potential (ERP) registration has the advantage of complex stimuli processing visualization.…”

mentioning

confidence: 99%

Patients With Better Outcome Have Higher ERP Response to Emotional Auditory Stimuli

Portnova

Подлепич

Skorokhodov

2022

Journal of Clinical Neurophysiology

View full text Add to dashboard Cite

Purpose: Accuracy of outcome prognosis is one of the most important tasks of coma arousal therapy. Reactions toward sensory stimuli are the most significant predictor of conscience and cognitive functions restoration after a brain injury. A paradigm that includes ERP registration has the advantage of detailed stimuli processing visualization. The authors aimed to investigate perception and distinguishing of emotionally significant sounds (crying and laughter) in coma patients with different consciousness restoration prognosis.Methods: EEG was recorded in 24 comatose patients with different outcomes (scored with Glasgow Outcome Scale-Extended) and 32 healthy volunteers. The authors presented sounds of crying and laughter. ERPs for sound stimulation were calculated.Results: An analysis of the correlation of ERP components and Glasgow Outcome Scale-Extended score was performed. P200 (r ¼ 0.6, P ¼ 0.0014) and N200 amplitudes (r ¼ 20.56, P ¼ 0.0037) for emotional sounds correlated with the Glasgow Outcome Scale-Extended score. The significant differences of P300 and N400 amplitudes corresponded to differences of response between sounds of crying and laughter in subjects of the control group. Unlike the control group, comatose participants with good outcome produced similar electrical activity toward pleasant and unpleasant emotional stimuli.Conclusions: Comatose patients with good outcome produced more prominent ERP for emotional sounds. Even the good outcome participants were unable to distinguish emotional sounds of different moods, which indicate the preservation of solely robust mechanisms of sound processing. N200 and P200 amplitudes for emotional stimuli correlated significantly with outcome prognosis in coma patients.

show abstract

P300 Event-Related Potentials Differentiate Better Performing Individuals With Traumatic Brain Injury: A Preliminary Study of Semantic Processing

Cited by 9 publications

References 29 publications

Relationship between cognitive processing, language and verbal fluency among elderly individuals

Relationship between cognitive processing, language and verbal fluency among elderly individuals

Efficacy of Combined XingZhi‐YiNao Granules and Hyperbaric Oxygen Therapy for Cognition and Motor Dysfunction in Patients with Delayed Encephalopathy after Acute Carbon Monoxide Poisoning

Patients With Better Outcome Have Higher ERP Response to Emotional Auditory Stimuli

Contact Info

Product

Resources

About