P300 em sujeitos com perda auditiva

Abstract

Background: behavioral and electrophysiological evaluations contribute to the understanding of the hearing system and to the intervention process. Aim: to investigate the occurrence of P300 in subjects with congenital severe to profound hearing loss, according to the variables of gender, age and hearing loss level. Method: the design of this research is a descriptive transversal study. Twenty-nine subjects, 15 male and 14 female, ranging in age from 11 to 42 years, were evaluated. Inclusion criteria were: to have at least 11 years of age and no more than 45 years; to have the diagnosis of congenital severe to profound sensorineural hearing loss; to have no other disorder; and absence of central hearing loss or any other auditory conductive disorder. The first stage consisted of an auditory behavioral and physiological evaluation, including: pure tone audiometry (air and bone conduction measures), speech audiometry, SDT (Speech Detection Threshold) and functional gain measures for the subjects using hearing aids, and immittance measures -tympanometry and acoustic reflexes thresholds; transient evoked otoacoustic emissions (TEOAE); distortion product otoacoustic emissions (DPOAE). The electrophysiological evaluation was the fourth stage of the study and included: auditory brainstem response (ABR) and late latency response (P300). Results: P300 was obtained for 17 out of the 29 subjects. Mean latency and amplitude were 326.97 ms and 3.76 V, respectively. A statistical significant difference was observed for latency when considering the variable age (electrode CzA2 p < 0.003 and CzA1 p < 0.02) and for amplitude when considering the variable hearing loss level (p < 0.0015). Conclusion: P300 can be recorded in subjects with hearing loss.

Auditory Evoked Potentials with Different Speech Stimuli: a Comparison and Standardization of Values

“…There is a variation in the literature of 1.7 to 20uV, and many authors do not use these values in interpreting the results because of the wide range of values described. 28 In our study, we also found ample variation for the P300's amplitude in the values between all the different speech tokens.…”

Monitoring auditory cortical plasticity in hearing aid users with long latency auditory evoked potentials: a longitudinal study

“…Individuals (children and adults) with severe or profound congenital hearing loss showed 58.6% presence of P300. Individuals with profound hearing loss showed lower amplitudes than those with severe hearing loss, but there were no differences in latency 11 .…”

Auditory evoked potential P300 in adults: reference values

“…P300 values very widely between studies, both in test and control groups, ( 20 ) and may range from 1.7 to 20uV. ( 21 ) According to some studies, amplitude is not a relevant parameter in data analysis. ( 22 , 23 )…”