P300 correlates with tDCS response in minimally conscious state patients

Zhang, Ye; Chen, Weiguan; Zhang, Tiantian; Du, Jing; Li, Rui; Huo, Renchao; Song, Weiqun

doi:10.1016/j.neulet.2022.136534

Cited by 4 publications

(10 citation statements)

References 31 publications

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“…The modulations induced by neurostimulation techniques could also be a promising approach to better differentiating the DoC population. In this framework, 12 studies employed TMS and tDCS, analysing either the changes in various cortical excitability indexes (Lapitskaya et al, 2013; Naro, Leo, Filoni, et al, 2015; Naro, Calabrò, Russo, et al, 2015; Naro, Leo, Cannavò, et al, 2015; Naro, Leo, et al, 2016; Naro et al, 2018; Odinak et al, 2014; Zhang et al, 2020, 2022) or focusing on natural rhythms modulation (Naro et al, 2017; Naro, Bramanti, et al, 2016; Naro, Leo, Bramanti, & Calabrò, 2015; Pisani et al, 2015).…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the first set of works, repetitive TMS (rTMS) applied over the motor cortex resulted in lower amplitude of motor and sensory evoked potentials in DoC patients (Lapitskaya et al, 2013; Odinak et al, 2014) with positive correlations between the magnitude of the TMS' induced effects and the CRS‐R scores. Notably, tDCS and rTMS modulations differentiated DoC subgroups (Naro, Leo, Filoni, et al, 2015; Naro, Calabrò, Russo, et al, 2015; Naro, Leo, Cannavò, et al, 2015; Naro, Leo, et al, 2016; Naro et al, 2018; Zhang et al, 2020, 2022).…”

Section: Resultsmentioning

confidence: 99%

“…Twenty-eight studies aimed to use a multimodal approach for better differentiating the DoC diagnoses (Bekinschtein et al, 2011;Braiman et al, 2018;Candia-Rivera et al, 2021;Carriére et al, 2020;Chennu et al, 2013;Coleman et al, 2005;Curley et al, 2018;Edlow et al, 2017;Forgacs et al, 2014;Gibson et al, 2016;Gofton et al, 2009;Hermann et al, 2021;Li et al, 2015;Lutkenhoff, Nigri, et al, 2020;Lapitskaya et al, 2013;Naro, Leo, Filoni, et al, 2015;Naro, Calabrò, Russo, et al, 2015;Naro, Leo, Cannavò, et al, 2015;Naro et al, 2017Naro et al, , 2018Odinak et al, 2014;Rudolf et al, 1999;Sattin et al, 2021;Zhang et al, 2020Zhang et al, , 2022. For this purpose, patients have been either involved in active MRI tasks and/or EEG recording sessions (Bekinschtein et al, 2011;Braiman et al, 2018;Carriére et al, 2020;Chennu et al, 2013;Curley et al, 2018;Edlow et al, 2017;Forgacs et al, 2014;Gibson et al, 2016) or passively stimulated with auditory, visual or painful stimuli (Gofton et al, 2009;Hermann et al, 2021;Li et al, 2015;Sattin et al, 2021) or by means of TMS and tDCS …”

Section: Studies Focusing On the Differential Diagnosis Among Docsmentioning

confidence: 99%

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Multimodal approaches supporting the diagnosis, prognosis and investigation of neural correlates of disorders of consciousness: A systematic review

Gallucci,

Varoli,

Del Mauro

et al. 2023

Eur J of Neuroscience

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The limits of the standard, behaviour‐based clinical assessment of patients with disorders of consciousness (DoC) prompted the employment of functional neuroimaging, neurometabolic, neurophysiological and neurostimulation techniques, to detect brain‐based covert markers of awareness. However, uni‐modal approaches, consisting in employing just one of those techniques, are usually not sufficient to provide an exhaustive exploration of the neural underpinnings of residual awareness. This systematic review aimed at collecting the evidence from studies employing a multimodal approach, that is, combining more instruments to complement DoC diagnosis, prognosis and better investigating their neural correlates. Following the PRISMA guidelines, records from PubMed, EMBASE and Scopus were screened to select peer‐review original articles in which a multi‐modal approach was used for the assessment of adult patients with a diagnosis of DoC. Ninety‐two observational studies and 32 case reports or case series met the inclusion criteria. Results highlighted a diagnostic and prognostic advantage of multi‐modal approaches that involve electroencephalography‐based (EEG‐based) measurements together with neuroimaging or neurometabolic data or with neurostimulation. Multimodal assessment deepened the knowledge on the neural networks underlying consciousness, by showing correlations between the integrity of the default mode network and the different clinical diagnosis of DoC. However, except for studies using transcranial magnetic stimulation combined with electroencephalography, the integration of more than one technique in most of the cases occurs without an a priori‐designed multi‐modal diagnostic approach. Our review supports the feasibility and underlines the advantages of a multimodal approach for the diagnosis, prognosis and for the investigation of neural correlates of DoCs.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Studies Focusing On the Differential Diagnosis Among Docsmentioning

confidence: 99%

See 1 more Smart Citation

Multimodal approaches supporting the diagnosis, prognosis and investigation of neural correlates of disorders of consciousness: A systematic review

Gallucci,

Varoli,

Del Mauro

et al. 2023

Eur J of Neuroscience

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“…In the protocol of tDCS, target is one of the important parameters. Most studies were initially conducted with single‐target therapy, targeting the dorsolateral prefrontal cortex (DLPFC), primary motor cortex (M1), and precuneus 11–14,16–18,20–27,30–32 . The DLPFC has been a hot spot for tDCS‐stimulated target selection 12–14,17,18,22–24,26,30–32 .…”

Section: Update On Transcranial Direct Current Stimulationmentioning

confidence: 99%

“…Thus, an increasing number of studies were designed to investigate the effects in the form of multiple repeated sessions. In the last 5 years, 14 related papers were published 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 (Table 1 ). The number of sessions was not consistent, varying from 10 to 80 times, and the results were inconsistent.…”

Section: Update On Transcranial Direct Current Stimulationmentioning

confidence: 99%

An update on noninvasive neuromodulation in the treatment of patients with prolonged disorders of consciousness

Wan,

Zhang,

et al. 2024

CNS Neurosci Ther

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BackgroundWith the improvement of emergency techniques, the survival rate of patients with severe brain injury has increased. However, this has also led to an annual increase in the number of patients with prolonged disorders of consciousness (pDoC). Hence, recovery of consciousness is an important part of treatment. With advancing techniques, noninvasive neuromodulation seems a promising intervention. The objective of this review was to summarize the latest techniques and provide the basis for protocols of noninvasive neuromodulations in pDoC.MethodsThis review summarized the advances in noninvasive neuromodulation in the treatment of pDoC in the last 5 years.ResultsVariable techniques of neuromodulation are used in pDoC. Transcranial ultrasonic stimulation (TUS) and transcutaneous auricular vagus nerve stimulation (taVNS) are very new techniques, while transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are still the hotspots in pDoC. Median nerve electrical stimulation (MNS) has received little attention in the last 5 years.ConclusionsNoninvasive neuromodulation is a valuable and promising technique to treat pDoC. Further studies are needed to determine a unified stimulus protocol to achieve optimal effects as well as safety.

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Effects of parietal repetitive transcranial magnetic stimulation in prolonged disorders of consciousness: A pilot study

Wan,

Zhang,

et al. 2024

Heliyon

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P300 correlates with tDCS response in minimally conscious state patients

Cited by 4 publications

References 31 publications

Multimodal approaches supporting the diagnosis, prognosis and investigation of neural correlates of disorders of consciousness: A systematic review

Multimodal approaches supporting the diagnosis, prognosis and investigation of neural correlates of disorders of consciousness: A systematic review

An update on noninvasive neuromodulation in the treatment of patients with prolonged disorders of consciousness

Effects of parietal repetitive transcranial magnetic stimulation in prolonged disorders of consciousness: A pilot study

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