P3‐474: Automatic Detection of Linguistic Indicators as a Means of Early Prediction of Alzheimer's and of Related Dementias: A Cross‐linguistics Analysis

Abstract

in dementia, key evidence to establish its stability. The aim of the present study is to assess the temporal stability of WAT-R in patients with dementia. Methods: Thirtytwo patients with a diagnosis of dementia according to the NIA-AA (McKhann et al., 2011) CDR 1 and 2, and 34 subjects classified as normal according to a standard neuropsychological evaluation and neurological consultation has participated. The participants were assessed with a neuropsychological evaluation in two moments (interval from 1 to 6 years). We analyzed the results of the cognitive (ACE, MMSE) and executive (Ineco Frontal Screening) screening tests, and the WAT-R at moment 1 and 2. Results:At the dementia group, significant differences were found between evaluation 1 and 2 in the cognitive screening measures (MMSE t¼3.7 p<.001, ACE-R t¼3.2 p<.001) but not in the WAT-R (t¼0.3 p¼.78) nor in the Executive Screening test (IFS t¼1.9 p¼.06). In the healthy adults group, no significant differences were found in the cognitive (MMSE t¼0.7 p¼.49, ACE t¼1.5 p¼.15) and executive screening tests (t¼0.2 p¼.87) nor in the WAT-R (t¼1.6 p¼.12). Conclusions: Our data suggest the stability of the WAT-R in patients with dementia as well as in subjects without cognitive impairment, suggesting an efficient estimator of premorbid intelligence in aging.

Pronoun reference in Greek speakers with Alzheimer's Disease

“…Furthermore, we found a higher pronoun-to-noun ratio and interrogative-to-total pronouns ratio for our AD group across speech samples. The higher pronoun-to-noun ratio is in accordance with the findings of Khodabaksh et al (2015), Fraser et al (2016), Kavé and Dassa (2018) and Rentoumi et al (2018). Moreover, a correlation between specific types of speech samples and pronoun type was attested within the AD group.…”

“…However, pronoun overuse in our data was not correlated with a working memory impairment contra Almor's Informational Load Hypothesis (ILH) and Working Memory Impairment Hypothesis (Almor et al, 1999), as well as contra Kavé and Levy (2003a). In addition, a higher pronoun-to-noun ratio was observed which corroborated the findings of Khodabaksh et al (2015), Fraser et al (2016), Kavé and Dassa (2018) and Rentoumi et al (2018). A higher pronoun-to-noun ratio was related to a naming deficit following Fraser et al (2016) and Kavé and Goral (2016).…”

“…),Fraser et al (2016),Kavé and Dassa (2018) andRentoumi et al's (2018) results but regardless of the kind of speech sample.…”

“…Nevertheless, the pronoun-to-noun ratio was extracted as a measure in another cross-linguistic study (Rentoumi et al 2018). Rentoumi et al ( 2018) 42 conducted a crosslinguistic computational analysis of Greek and English (US and UK) spontaneous speech samples extracted from oral descriptions of the Cookie-Theft picture description task.…”

Multilingual prediction of

“…There has been very little prior work on multilingual or cross-lingual dementia classification. Rentoumi et al (2018) presented preliminary results suggesting that some language features from CTP samples could transfer across Greek and English, but did not report classification results. Fraser et al (2018b) studied a related task of detecting mild cognitive impairment (MCI), and found that classification results could be improved in both English and Swedish by incorporating multilingual topic modelling into the feature extraction pipeline; however, they did not consider multilingual classification directly.…”