Abstract:Introduction: Chimerism analysis of recipient and donor cells enables the assessment of engraftment, minimal residual disease, and early detection of relapse post hematopoietic stem cell transplantation (HSCT). This is the first study to evaluate the use of two novel multiplex next generation sequencing (NGS) chimerism assays. Methods: DNA extracted from peripheral blood samples with known mixed chimerism percentages were used in two multiplex NGS chimerism assays following manufacturer's instructions to asses… Show more
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