P2B.16: Secondary Prophylaxis for Catheter Related Thrombosis in Pediatric Intestinal Failure – Comparison of Short vs. Long Term Anticoagulation Prophylaxis Protocols

Schmidt, M; Wendel, Danielle; Horslen, Simon; Lane, Erin R.; Brandão, Leonardo R.; Gottschalk, Emily; Belza, Christina; Courtney‐Martin, Glenda; Wales, Paul W.; Avitzur, Yaron

doi:10.1097/01.tp.0000575624.63648.4e

Cited by 1 publication

(2 citation statements)

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“…140,141 The use of long-term anticoagulant prophylaxis has not been widely recommended in current practice guidelines; however, retrospective reviews have suggested a benefit at preventing thrombi in both adult and pediatric populations. 142,143 At present, there are no predictive factors identifying children or adults at risk of developing thrombi, and prophylaxis prior to a sentinel event is not currently recommended. In patients who have developed a thrombus, however, clinicians should consider anticoagulant prophylaxis to protect long-term vascular access.…”

Section: Thrombosismentioning

confidence: 99%

“…Deep vein thrombosis may, in part, be related to the smaller caliber of blood vessels relative to CVC size 140,141 . The use of long‐term anticoagulant prophylaxis has not been widely recommended in current practice guidelines; however, retrospective reviews have suggested a benefit at preventing thrombi in both adult and pediatric populations 142,143 . At present, there are no predictive factors identifying children or adults at risk of developing thrombi, and prophylaxis prior to a sentinel event is not currently recommended.…”

Section: Introductionmentioning

confidence: 99%

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Intestinal failure among adults and children: Similarities and differences

Belza

Wales

2023

Nut in Clin Prac

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Intestinal failure (IF) is a complex medical condition that is caused by a constellation of disorders, resulting in the gut's inability to adequately absorb fluids and nutrients to sustain hydration, growth, and survival, thereby requiring the use of parenteral fluid and/or nutrition. Significant advancements in intestinal rehabilitation have resulted in improved survival rates for individuals with IF. There are distinct differences, however, related to etiology, adaptive potential and complications, and medical and surgical management when comparing children with adults. The purpose of this review is to contrast the similarities and differences between these two distinct groups and provide insight for future directions, as a growing population of pediatric patients will cross into the adult world for IF management.

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