P2520Predictors of success of biofeedback in the rehabilitation of patients after acute myocardial infarction

Abstract

In current work, it were evaluated clinical predictors for the success of biofeedback (BF) sessions during cardiorespiratory training (CT) by cardiac rhythm for the development of cardiorespiratory synchronization (CRS) in addition to standard therapy in patients with myocardial infarction (MI) in early periods. The study included 50 patients with uncomplicated MI on 6–10 days of disease. 21 patients developed stable CRS during training in the hospital. All patients underwent general clinical examination: control of blood pressure, heart rate, ECG, echocardiography, assessment of heart rate variability (HRV). Using of discriminant analysis of initial clinical parameters, heart rate variability parameters and cardiorespiratory training, a mathematical model was constructed that allows predict the success of CT in patients in early period of MI with a probability of 96.7%. f = −8.85 + 0.21X1 + 3.87X2 − 4.96X3 − 1.72X4 + 3.5X5 − 1.57X6 − 1.58X7 − 0.69X8 + 1.63X9 + 0.008X10 − 0.069X11 + 0.089X12 + 2.71X13 − 2.61X14 + 5.65X15 where X1 is the left ventricular ejection by echocardiography, X2 is the number of MI, X3 is the presence of previous history of coronary artery disease, X4 is diabetes, X5 is smoking, X6 is thrombolysis, X7 is coronary artery stenting, X8 is SDNN by HRV, X9 – CV by HRV, X10 – TP by HRV, X11 – HR in the first active test, X12 – diastolic blood pressure in the first inactive test, X13 – change in the HRV in the first active test as compared to the first inactive test, X14 – change in systolic blood pressure in the last inactive test compared to with the first inactive test, X15 – change in diastolic blood pressure in the last inactive test compared to with the first inactive test. The threshold value is f = −0.21. If the patient's IM value is greater than the threshold value, the patient will belong to the CRS successful group. If the patient's IM value is less than the threshold value, the patient will belong to the CRS unsuccessful group. Conclusion the developed mathematical model allows predict the effectiveness of cardiorespiratory training in patients in early period of uncomplicated MI.