P20 - Split-Ring Resonator for measuring low amounts of glutamic acid in pure water

Dehning, Kirsten J.; Gossmann, A.; Hitzemann, Moritz; Zimmermann, Stefan

doi:10.5162/16dss2022/p20

Cited by 1 publication

(1 citation statement)

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“…The SRR shown in Figure 2 is used within this work and consists of two microstrip lines on a printed circuit board (PCB) with FR4 as dielectric material and a thickness of 1.4 mm. A detailed explanation of the SRR including simulations and experiments is given in [ 27 ]. To prevent liquids from breaking into the dielectric material of the printed circuit board, the surface at the top except the microstrip lines is coated with a solder mask with a thickness of about 25 µm.…”

Section: Methodsmentioning

confidence: 99%

Split-Ring Resonator Based Sensor for the Detection of Amino Acids in Liquids

Dehning

Hitzemann

Gossmann

et al. 2023

Sensors

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Amino acids belong to the most important compounds for life. They are structural components of proteins and required for growth and maintenance of cells. Essential amino acids cannot be produced by the organism and must be ingested through the nutrition. Therefore, the detection of amino acids is of great interest when analyzing cell culture media and nutrition. In this work, we present a split-ring resonator as a simple but sensitive detector for amino acids. Split-ring resonators are RLC resonant circuits with a split capacitance and thus a resonance frequency that depends on the electromagnetic properties of a liquid sample at the split capacitance. Here, the split capacitance is an interdigital structure for highest sensitivity and covered with a fluidic channel for flow through experiments. First measurements with a vector network analyzer show detection limits in the range from 105 µM for glutamic acid to 1564 µM for isoleucine, depending on the electromagnetic properties of the tested amino acids. With an envelope detector for continuous recording of the resonance frequency, the split-ring resonator can be used in ion chromatography. At a flow rate of 0.5 mL/min, it reaches limits of detection of 485 µM for aspartic acid and 956 µM for lysine.

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Section: Methodsmentioning

confidence: 99%