P2.16-019 Improving Survival with a Lymph Node (LN) Collection Kit for Non-Small Cell Lung Cancer (NSCLC) Resections

Abstract

were 329 cases of PCs: 217 (66%) typical (TC) and 112 (34%) atypical (AC) carcinoids, with a median follow-up time of 7,6 years. There were 230 females (69,9%) and 99 males (30,1%). The most common symptoms were cough (38,7%), dyspnea (15,9%) and hemoptysis (14%). No patients showed a carcinoid syndrome. There was no correlation between smoking status and PCs. The majority of patients were in stage I disease (67,4%), only 6,4% in stage III and IV (6,4%). Involvement of lymph nodes was present in 49 cases (14,9%), N1-34 (10,3%) and N2 e 15 (4,6%). Infiltration of bronchial or vessel margin (R1) was revealed in 10 cases (3%). Surgical treatment consisted of: 247 lobectomies (75,1%), 30 pneumonectomies (9,1%), 36 bilobectomies (10,9%), 5 anatomic segmentectomies (1,5%), 8 wedge resections (2,4%), 3 e bronchoplastic procedures without lung resection (0,9%). Radical mediastinal lymphadenectomy was added in all cases. The number of death among the patients with TC and AC was 7 (6,3%) and 31 (14,3%) respectively. Kaplan-Meier 1-, 5-, 10-and 15-year overall survivals for the entire group were 98,8%, 92,8%, 86,8% and 78,6% respectively. Conclusion: PCs are tumors with an excellent prognosis, even in the presence of metastases in lymph nodes and positive surgical margin. None of the symptoms and stage of tumors as well as the distance of the tumor from the surgical margin did not affect significantly the overall survival. The age of patients, the type of operation and performance status (ECOG score) had vital importance for overall survival. Surgical resection is the best and adequate therapy for PCs with high overall survival and disease-free survival but longtime observation is necessary.