P2.05-010 Stereotactic Radioterapy (SBRT) for Primary and Metastatic Lung Tumors in Elderly Patients

Abstract

tumor and mediastinum and a boost of 20Gy to all gross disease. All patients also received platinum based doublet regimen concurrently. After CRT, the patients were re-evaluated in the resectability and underwent surgery. We analyzed tumor volume reduction ratio near the end of radiation therapy. All patients were classified by their lung condition about emphysematous and interstitial changes with CT images before treatment into three degree (slight / moderate / severe). Patients with grade 2 or worse RP were ebaluated with their Dose-Volume Histofram(DVH) parameteres of both lungs. Results: The median follow up time was 73.9 months. The 3-year and 5-year overall survival rates were 44.8% and 33.0% in all patients, and 74.7% and 64.7% in patients with CRT followed by surgery. The 3-year and 5-year local control rates were 68.8% and 49.0%, respectively, in all patients. More than 50 % volume reduction was observed in 73.2 % of patients surviving over 2-years, but 32.3% of these good responder had local failure. Grade 2 or worse RP were observed in 70 patients (27%), grade3 in 11 patients (4%), grade 5 in 3 patients (1%).