P2.03b-025 Mutation Profile and Histology Subtype According to IASLC/ERS/ATC as Risk Factors for Brain Metastases in Lung Adenocarcinoma

Abstract

Background: Brain metastases (BM) are common among patients with adenocarcinoma, affecting treatment response, quality of life and overall survival (OS). We examine the impact of the main histological pattern and the genetic alterations in EGFR and ALK on the incidence of BM in patients with advanced non-small cell lung cancer (NSCLC).