P196 Risk of venous thromboembolism according to disease activity, hospitalisation, or surgry in inflammatory bowel disease: a nationwide cohort study

Things We Do for No Reason™: Withholding pharmacologic venous thromboembolism prophylaxis in hospitalized patients with inflammatory bowel disease

“…The crude rate of VTE during hospitalization was especially high among those with ulcerative colitis (21.0 per 1000 hospitalizations) compared to non‐IBD admissions (13.8 per 1000 hospitalizations; p < .0001) 9 . This elevated risk is observed even when IBD patients are hospitalized for non‐IBD associated indications, wherein a 2019 Korean nationwide cohort study showed a VTE incidence of 9.85 per 1000 person‐years in this population, with a hazard ratio of 12.97 compared to controls 12 . In comparison, known patient‐related risk factors like prior VTE or malignancy increase VTE risks eight‐ and three‐fold, respectively 13 …”

“…9 This elevated risk is observed even when IBD patients are hospitalized for non-IBD associated indications, wherein a 2019 Korean nationwide cohort study showed a VTE incidence of 9.85 per 1000 person-years in this population, with a hazard ratio of 12.97 compared to controls. 12 In comparison, known patient-related risk factors like prior VTE or malignancy increase VTE risks eight-and three-fold, respectively. 13 Furthermore, patients with IBD who develop VTE during a hospitalization incur a longer length of stay (LOS), higher hospital costs, and excess in-hospital mortality.…”

The Journey Through the Pathogenesis and Treatment of Venous Thromboembolism in Inflammatory Bowel Diseases: A Narrative Review

“…In particular, IBD-related surgery conferred a higher thrombotic risk both during hospitalization and post-discharge, even when compared with non-IBD-related surgery for colorectal cancer. [66][67][68] The highest risk of VTE is present within the first 2 weeks of hospital discharge, with 61% of postoperative venous thrombosis occurring within that period 69 (►Table 4).…”

Venous Thromboembolism in Patients with Inflammatory Bowel Disease

“…It encompasses deep vein thrombosis (DVT) and pulmonary embolism (PE). While DVT usually occurs in the deep veins of the lower extremities, it may also occur in deep veins of the upper extremities, mesenteric veins, portal vein, hepatic veins (Budd-Chiari syndrome), and cerebral veins, as seen in Figure 1 [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ]. In the United States, each year, more than half a million hospitalizations have been linked to VTE [ 16 ].…”