P168. Osteolysis in Posterior and Transforaminal Lumbar Interbody Fusion with Bone Morphogenic Protein-2

Mengele in America: Human Experimentation and the Walter Reed Connection

“…Other data provided by government regulators and other medical publications documented that up to 50% of patients treated with InFuse experienced significant complications and side effects, including bone osteolysis and ectopic bone growth, inflammatory reactions including radiculitis, graft subsidence and migration, infertility in men, and concerns regarding carcinogenesis. 11 Contrary to this has been the experience of a single neurosurgeon spine specialist (the author), who, in a series of fusion cases extending from 1992 to 2010 and involving more than 700 patients, has utilized autologous bone marrow (rather than bioengineered substances) and locally harvested autologous bone for the purpose of enhancing bone fusion. Autologous bone marrow actually contains bone morphogenetic protein and is even better than bone morphogenetic protein because it also contains stem cells to further power the osteogenic process.…”