“…Inactivation of p16 was noted in neoplastic cell lines, which may suggest its antineoplastic effect (33). On the other hand, several authors have demonstrated high expression of the protein in malignant tumours, such as uterine carcinoma and adenocarcinoma, lymphatic leukaemia, malignant melanoma, and squamous cell carcinoma (1,39,44). Moreover, the expression was found to be correlated with the grade of tumour malignancy (1).…”