HemaSphere
 2023
DOI: 10.1097/01.hs9.0000972380.62376.53
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P1373: Uncovering Upsides and Pitfalls of Base and Prime Editing in Hematopoietic Stem Cells

Martina Fiumara
1
,
Samuele Ferrari
2
,
Attya Omer-Javed
3
et al.

Abstract: Emerging base and prime editing (BE/PE) may provide safer and more precise genetic engineering than nucleasebased approaches bypassing the dependence on DNA double strand breaks (DSBs).

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