P1‐352: What Can the Mild Behavioral Impairment Checklist (Mbi‐c) Tell Us About Cognition and Behavior in Parkinson's Disease?

Monchi, Oury; Ismail, Zahinoor; Kibreab, Mekale; Yoon, Eunjin; Kathol, Iris; Hammer, Tracy; Cheetham, Jenelle

doi:10.1016/j.jalz.2018.06.360

Cited by 2 publications

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“…Further, the MBI-C has demonstrated internal consistency, test-retest reliability (Mallo et al, 2018c), and discriminative validity from the NPI (Kang et al, 2018;Mallo et al, 2018c). In terms of imaging and biomarker validations, the MBI-C is associated with worsening cognition and temporal lobe atrophy in those with Parkinson's Disease (Monchi et al, 2018). Very recent data has correlated MBI-C score with PET ß-amyloid burden, in those with normal cognition, again supporting the utility of the MBI-C in case finding for early stage neurodegenerative disease in advance of overt cognitive impairment (Lussier et al, 2019).…”

Section: Introductionmentioning

confidence: 95%

Profile of mild behavioral impairment and factor structure of the Mild Behavioral Impairment Checklist in cognitively normal older adults

Creese

Griffiths

Brooker

et al. 2019

Int. Psychogeriatr.

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ABSTRACTObjectives:In this large population study, we set out to examine the profile of mild behavioral impairment (MBI) by using the Mild Behavioral Impairment Checklist (MBI-C) and to explore its factor structure when employed as a self-reported and informant-rated tool.Design:This was a population-based cohort study.Setting:Participants were recruited from the Platform for Research Online to Investigate Genetics and Cognition in Aging study (https://www.protect-exeter.org.uk).Participants:A total of 5,742 participant-informant dyads participated in the study.Measurements:Both participants and informants completed the MBI-C. The factor structure of the MBI-C was evaluated by exploratory factor analysis.Results:The most common MBI-C items, as rated by self-reported and informants, related to affective dysregulation (mood/anxiety symptoms), being present in 34% and 38% of the sample, respectively. The least common items were those relating to abnormal thoughts and perception (psychotic symptoms) (present in 3% and 6% of the sample, respectively). Only weak correlations were observed between self-reported and informant-reported MBI-C responses. Exploratory factor analysis for both sets of respondent answers indicated that a five-factor solution for the MBI-C was appropriate, reflecting the hypothesized structure of the MBI-C.Conclusion:This is the largest and most detailed report on the frequency of MBI symptoms in a nondementia sample. The full spectrum of MBI symptoms was present in our sample, whether rated by self-reported or informant report. However, we show that the MBI-C performs differently in self-reported versus informant-reported situations, which may have important implications for the use of the questionnaire in clinic and research.

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Section: Introductionmentioning

confidence: 95%

Profile of mild behavioral impairment and factor structure of the Mild Behavioral Impairment Checklist in cognitively normal older adults

Creese

Griffiths

Brooker

et al. 2019

Int. Psychogeriatr.

Self Cite

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show abstract

Section: Introductionmentioning

confidence: 95%

Profile of Mild Behavioral Impairment and Factor Structure of the Mild Behavioral Impairment Checklist in Cognitively Normal Older Adults

Creese¹,

Griffiths²,

Brooker³

et al. 2019

Preprint

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Objectives: In this large population study we set out to examine the profile of Mild Behavioral Impairment using the Mild Behavioral Impairment Checklist (MBI-C), and determine its factor structure when employed as a self-report and informant rated tool.Design: Population based cohort study. Setting: Online testing via the PROTECT study (http://www.protectstudy.org.uk)Participants: 5,742 participant-informant dyads.Measurements: Both participants and informants completed the MBI-C. The factor structure of the MBI-C was evaluated by exploratory factor analysis (EFA).Results: The most common MBI-C items as rated by self-report and informants related to affective dysregulation (mood/anxiety symptoms), being present in 34% and 38% of the sample respectively. The least common were items relating to abnormal thoughts and perception (psychotic symptoms) (present in 3 and 6% of the sample respectively). There were only weak correlations between self-report and informant-rated MBI-C responses. EFA for both sets of respondent answers indicated a five-factor solution for the MBI-C was appropriate, reflecting the structure of the MBI-C.Conclusion: This is the largest and most detailed report on the frequency of MBI symptoms in the general population. The full spectrum of MBI symptoms was present in our sample, whether rated by self-report or informant report. However, we show that the MBI-C performs differently in self-rated versus informant-rated situations, which may have important implications for the use of the questionnaire in clinic and research.

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P1‐352: What Can the Mild Behavioral Impairment Checklist (Mbi‐c) Tell Us About Cognition and Behavior in Parkinson's Disease?

Cited by 2 publications

References 0 publications

Profile of mild behavioral impairment and factor structure of the Mild Behavioral Impairment Checklist in cognitively normal older adults

Profile of mild behavioral impairment and factor structure of the Mild Behavioral Impairment Checklist in cognitively normal older adults

Profile of Mild Behavioral Impairment and Factor Structure of the Mild Behavioral Impairment Checklist in Cognitively Normal Older Adults

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