P1-271 Prevalence, risk factors and patterns of chronic kidney disease in a rural community in South West Nigeria

Oluyombo, Rotimi; Akinsola, A; Ayodele, Olugbenga Edward; Onayade, Adedeji; Arogundade, FA; Sanusi, Abubakr A.; Akinwusi, PO; Okunola, OO

doi:10.1136/jech.2011.142976e.63

Cited by 29 publications

(65 citation statements)

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“…Similar findings have been reported from other studies conducted in low-and middle-income countries, whereby hypertension has been reported to be the leading cause of CKD. 2,9,10,13,14 However, these findings are contrary to a community-based study conducted in Northern Tanzania that showed that nearly half (49.2%) of the cases of CKD were not associated with any of the measured risk factors of hypertension, diabetes, or HIV. 16 This discrepancy calls for more research into other causes of CKD, including the use of local herbs and medicines, which is very rampant in this area where this study was conducted.…”

Section: Discussioncontrasting

confidence: 70%

“…Similar findings have been reported from other studies whereby obesity and positive history of smoking were reported as risk factors for CKD. 14,[19][20][21] In this study obesity (BMI ≥30), diabetes mellitus and systolic hypertension were strongly associated with development of CKD (P<.001). Similar findings have been reported from other studies.…”

Section: Discussionmentioning

confidence: 95%

“…), with age, female gender, systolic blood pressure, and diabetes mellitus as predictors of CKD. 14 In a study of outpatients in North Western Tanzania, an alarmingly high prevalence (87.3%) of CKD was identified among adult patients attending diabetes mellitus clinic. 15 In a community-based study conducted in Northern Tanzania, the overall prevalence of CKD was found to be 7%; and, of these patients, 19.3% had hypertension alone, 14.0% had both diabetes and hypertension, 7.0% had diabetes alone, 7.0% had HIV alone, and 3.5% had both HIV and hypertension.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Risk Factors Associated With Chronic Kidney Disease Among Patients Presenting at a Haemodialysis Unit in Dodoma, Tanzania

Meremo

Masalu

Sabi

et al. 2018

EAHRJ

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Background: Chronic kidney disease (CKD) is a major public health problem worldwide, due to its epidemic proportions and the associated cardiovascular morbidity and mortality. However, data on the burden of CKD among patients attending hospitals in Tanzania are still limited. The aim of this study was to determine the prevalence and risk factors associated with CKD among patients presenting at the University of Dodoma (UDOM) haemodialysis unit in Tanzania. , a total of 1,395 patients presented at the UDOM haemodialysis unit with history of kidney disease. Of these patients, 1244 (89.2%) enrolled into this study, 651 (52.3%) of them were female. Almost two-thirds (n=792, 63.7%) of the patients were found to have CKD, 59.1% with an estimated glomerular filtration rate of <60 mL/min/1.73 m 2 . Among those who had CKD, 347 (43.8%) had hypertension, 241 (30.4%) had diabetic mellitus, 79 (10.0%) had chronic glomerulonephritis, 70 (8.8%) had hypertension and diabetes mellitus, 38 (4.8%) had HIV/AIDS, and 17 (2.1%) had hepatitis B. The median serum creatinine level was 222 lmol/L (interquartile range [IQR] 126 to 317), urea level was 14.5 mmol/L (IQR 5 to 24), hemoglobin was 11.0 g/dL (IQR 6.2 to 15.7), and body mass index was 27.1 kg/m 2 (IQR 17.3 to 36.8). Obesity, diabetes mellitus, and systolic hypertension were associated with developing CKD (P<.001). A total of 116 patients received haemodialysis during the study period.

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Section: Discussioncontrasting

confidence: 70%

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

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Prevalence and Risk Factors Associated With Chronic Kidney Disease Among Patients Presenting at a Haemodialysis Unit in Dodoma, Tanzania

Meremo

Masalu

Sabi

et al. 2018

EAHRJ

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“…There is a high rate of undiagnosed cardiovascular risk factors in Nigeria and the sub-region 89. The earlier the diagnosis is made the better the outcome, as this prevents progression to atherosclerosis, and worsening of non-conventional cardiovascular risk factors and associated end-organ damage, which is usually irreversible.…”

Section: Discussionmentioning

confidence: 99%

“…There have been reports of increased prevalence of CVD risk factors in Nigeria, with hypertension, diabetes, hyperlipidaemia and obesity as the leading modifiable causes 89. Studies have shown co-existence and interaction of these risk factors, causing them to become difficult-to-treat conditions, and resulting in serious complications and fatal outcomes 1011…”

Section: Introductionmentioning

confidence: 99%

Clustering of cardiovascular risk factors in semi-urban communities in south-western Nigeria

Oluyombo

Akinwusi

Olamoyegun

et al. 2016

CVJA

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SummaryBackgroundIn addition to poor socio-economic indices and a high prevalence of infectious diseases, there have been various reports of a rising prevalence of cardiovascular diseases, with associated morbidity and mortality in developing countries. These factors co-exist, resulting in a synergy, with serious complications, difficult-to-treat conditions and fatal outcomes. Hence this study was conducted to determine the clustering of cardiovascular disease risk factors and its pattern in semi-urban communities in south-western Nigeria.MethodsThis was a cross sectional study over seven months in 11 semi-urban communities in south-western Nigeria.ResultsThe total number of participants was 1 285 but only 1 083, with 785 (65%) females, completed the data. Participants were 18 years and older, and 51.2% were over 60 years. The mean age was 55.12 ± 19.85 years. There were 2.6% current cigarette smokers, 22% drank alcohol and 12.2% added salt at the table, while 2% had been told by their doctors they had diabetes, and 23.6% had hypertension. The atherogenic index of plasma was at a high-risk level of 11.1%. Elevated total cholesterol and low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol levels were seen in 5.7, 3.7 and 65.1%, respectively. Prevalence of hypertension was 44.9%, diabetes was 5.2%, obesity with body mass index (BMI) > 30 kg/m2 was 5.7%, and abdominal circumference was 25.7%. Prevalence of clusters of two, three, and four or more risk factors was 23.1, 15.5 and 8.4%, respectively. Increasing age 2.94 (95% CI: 1.30–6.67), BMI 1.18 (95% CI: 1.02–1.37), fasting plasma glucose level 1.03 (95% CI: 1.00– 1.05), albuminuria 1.03 (95% CI: 1.00–1.05), systolic blood pressure 1.07 (95% CI: 1.04–1.10), diastolic blood pressure 1.06 (95% CI: 1.00–1.11) and female gender 2.94 (95% CI: 1.30–6.67) showed increased odds of clustering of two or more cardiovascular risk factors.ConclusionClustering of cardiovascular risk factors is prevalent in these communities. Patterns of clustering vary. This calls for aggressive and targeted public health interventions to prevent or reduce the burden of cardiovascular disease, as the consequences could be detrimental to the country.

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Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study

Adedeji

Dairo

Nguku

et al. 2022

Pharmacology Res & Perspec

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Population‐based drug utilization studies are scanty in Nigeria. The aim was to determine the pattern and predictors of medication use among adults in the communities of Southwestern Nigeria. A cross‐sectional study was conducted among adults selected by multi‐stage sampling from Oyo State communities. The questionnaires, adapted from the WHO Students' Drug Use Questionnaire and previous studies, were pretested and interviewer administered. The respondents' socio‐demographic characteristics, the pattern of medication use, prescribers, and sources of drug acquisition were obtained. Binary logistic regression was used to determine the predictor of medications used. Of the 999 respondents, 501 resided in rural communities while 498 dwelled in urban areas. The mean (±SD) age of the respondents was 38 ± 15 years. The median (range)% prevalence of medication use were as follows: lifetime use, 58.2 (17.7–81.0); current use, 31.2 (8.9–65.9); and past use, 20.3 (9.2–28.9). Medications were mainly obtained from patent medicine stores, median (range%), 71 (65–80). The commonly used drugs were paracetamol, 626 (67.6); nonsteroidal anti‐inflammatory drugs, 174 (18.8); artemether/lumefantrine, 422 (68.2); ampicillin/cloxacillin, 220 (48.6); and chlorpheniramine, 59 (39.9). Factors predictive of current medication use, adjusted odd ratio (95% confidence interval) were as follows: antimalarial [male, 0.7 (0.5, 0.9)]; antibacterial [male, 0.6 (0.4–0.9)]; analgesics [married, 1.5 (1.1–2.2); presence of health facilities, 0.5 (0.3–0.7); and shorter distance to health facility, 1.5 (1.1–2.1)]. Antimalarials, antibacterial, and analgesics were commonly used and inappropriately obtained by adults in Southwestern Nigeria. Factors predictive of current medication use were gender, marital status, the presence of health facilities, and distance to health facilities. There is a need for more extensive countrywide medication use studies and enlightenment programs to ensure the appropriate use of medications.

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P1-271 Prevalence, risk factors and patterns of chronic kidney disease in a rural community in South West Nigeria

Cited by 29 publications

References 0 publications

Prevalence and Risk Factors Associated With Chronic Kidney Disease Among Patients Presenting at a Haemodialysis Unit in Dodoma, Tanzania

Prevalence and Risk Factors Associated With Chronic Kidney Disease Among Patients Presenting at a Haemodialysis Unit in Dodoma, Tanzania

Clustering of cardiovascular risk factors in semi-urban communities in south-western Nigeria

Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study

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