Abstract:Background: The substantia innominata (SI) forms part of the basal fore-brain that provides major cholinergic innervation to the cerebral cortex and hippocampus, and has an essential role in cognitive function. Cholin-ergic loss is a central feature of dementia with Lewy bodies (DLB) and contributes to the clinical symptom phenotype. The objective was to investigate grey matter (GM) and white matter (WM) changes in the SI from magnetic resonance (MR) images in DLB, Alzheimer's disease (AD) and healthy older su… Show more
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