P090 The association between height and serum lipids

Antioxidative, Metabolic and Vascular Medicinal Potentials of Natural Products in the Non-Edible Wastes of Fruits Belonging to the Citrus and Prunus Genera: A Review

“…In vivo, sub-chronic to chronic administration of lime peel powder or essential oil to hypercholesterolemic or HFD-fed animals ameliorated hyperlipidemia and hypercholesterolemic and reduced AI as well as fatty streaks in the coronary arteries and aorta [ 51 , 53 ]. In fact, cholesterol and TG were reduced to a normal or near-normal range, while the AI was reduced by 86%, suggesting the possible benefits of lime peel on vascular health.…”

Phytochemical Screening, Therapeutic Benefits, and Adverse Effects of Citrus aurantifolia - A Review

“…Abnormal cholesterol level is a significant risk factor of cardiovascular diseases, such as coronary heart failure, heart attack, and atherosclerosis, characterized by blockage of blood vessels with fat due to irregularly high total cholesterol (TC), triglyceride (TG), very low-density lipoprotein cholesterol (VLDL-c), and low-density lipoprotein cholesterol (LDL-c) levels, and low high-density lipoprotein cholesterol (HDL-c) levels, and is mainly caused by improper diet and lifestyle (Lin et al, 2019;Boshtam et al, 2013;Cyndi, Andriane, & Nur, 2016). Prolonged consumption of conventional anti-hypercholesterolemic drugs such as statin group can lead to some side effects, so it is generally recommended to incorporate a higher amount of fruits and vegetables into diets, and lime was said to be beneficial for prevention of this diseases (Lin et al, 2019;Boshtam et al, 2013;Cyndi, Andriane, & Nur, 2016).…”

“…Abnormal cholesterol level is a significant risk factor of cardiovascular diseases, such as coronary heart failure, heart attack, and atherosclerosis, characterized by blockage of blood vessels with fat due to irregularly high total cholesterol (TC), triglyceride (TG), very low-density lipoprotein cholesterol (VLDL-c), and low-density lipoprotein cholesterol (LDL-c) levels, and low high-density lipoprotein cholesterol (HDL-c) levels, and is mainly caused by improper diet and lifestyle (Lin et al, 2019;Boshtam et al, 2013;Cyndi, Andriane, & Nur, 2016). Prolonged consumption of conventional anti-hypercholesterolemic drugs such as statin group can lead to some side effects, so it is generally recommended to incorporate a higher amount of fruits and vegetables into diets, and lime was said to be beneficial for prevention of this diseases (Lin et al, 2019;Boshtam et al, 2013;Cyndi, Andriane, & Nur, 2016). Lin et al (2019) used a homogenous mixture of 500 gr powdered peel in 2 L deionized water, which was steam-distilled to retrieve the extract, dried with anhydrous sodium sulfate, and stored in -20 o C. The extract was then tested for anticholesterolemic effect with different extract concentrations on mice treated with cholesterol and lard diet; it reported a significant decrease in body weight when treated with a high fat-diet and each of lime essential oil concentration (0.744% and 2.232%) with an observable dose-dependent response.…”

“…In a study by Boshtam et al (2013), shadedried and blended lime peel powder and lime juice were used to assess the antiatherosclerosis effect in rabbits with a high-fat diet, which was divided into four intervention groups, negative control (normal diet), positive control (hypercholesterolemic diet), lime juicetreated + hypercholesterolemic diet, and lime peel-treated + hypercholesterolemic diet groups. The results showed that the groups treated with either lime juice and lime peel extract had a significant decrease in fatty streaks compared to the positive control group, which suggested the success of atherosclerosis inhibition.…”

“…High amounts of LDL and VLDL cholesterols are considered to be highly associated with atherosclerosis, in which oxidation of these cholesterols can form lipid peroxides and other reactive oxygen species, which causes more damage to the blood vessel (Lin et al, 2019;Boshtam et al, 2013). High cholesterol content also inhibits HMG-CoA reductase and HMG-CoA synthase, the main enzymes of cholesterol synthesis, and inhibits cellular uptake of cholesterol (Cyndi, Andriane, & Nur, 2016).…”