P069 Ontamalimab, a Fully Human Monoclonal Antibody Against Mucosal Addressin Cell Adhesion Molecule-1, Provides Sustained Exposure Following Long-Term Treatment in Patients With Ulcerative Colitis
Abstract:Introduction
Ontamalimab is a fully human immunoglobulin G2 monoclonal antibody against mucosal addressin cell adhesion molecule-1 in development for the induction and maintenance of clinical remission in patients with ulcerative colitis (UC). This study aimed to assess the long-term pharmacokinetics (PK) of ontamalimab in patients with UC, and the effects of concomitant medications on PK parameters.
Methods
A 12-week inducti… Show more
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