P05.06: Sonography features of ectopic pregnancy: three years experience in a London University Hospital

Abstract

Poster abstractsrespectively. There was no major complication, however, 4 cases required intensive therapy unit care and blood transfusion, with total blood loss over 3 litres. Two of these cases had successful laparoscopic management. Average hospital stay was 2 days. Conclusions: Our study showed that 6% non-tubal ectopic pregnancies accounted for all ectopic pregnancies in the unit. Experience at ultrasound diagnosis and laparoscopic technique can lead to earlier diagnosis and few operative failures needing laparotomy. In spite of potential morbidity, laparoscopic surgery should be considered for women requiring surgery where laparoscopic expertise available. Medical management should be considered where appropriate. P05.04Is the embryonic growth rate in the first trimester influenced by cigarette smoking? (TVS). All women were asked whether they were a smoker or nonsmoker and this was recorded at the first visit. All women with a viable singleton pregnancy in the 1 st trimester who had at least two CRL measurements were included in the final analysis. The embryonic growth rate was measured in mm/day calculated using the following formula: (CRL mm @ 2 nd scan -CRL mm @ 1 st scan)/(gestational age @ 1 st scan -gestational age @ 2 nd scan). Pvalues were calculated using Welch t-test for the difference between the mean embryonic growth rates in smokers vs. non-smokers. Results: 779 consecutive women presented to the EPU and were subsequently found to have a live intrauterine pregnancy. 467 women underwent a single scan, 186 had two scans, 38 had three scans and 7 had more than three scans. A total of 184 women had complete data including smoker information and embryonic growth rate. 21.5% of women were smokers. The mean embryonic growth rate in the non-smoker and smoker groups were 1.19 mm/day and 0.96 mm/day, respectively (P-value = 0.003). Conclusions: First trimester embryonic growth velocity is slower in women who smoke compared to non-smokers. This is the first study to demonstrate that early aberrant embryonic growth patterns could be related to cigarette smoking. P05.05Efficacy and safety of single dose methotrexate treatment for ectopic pregnancy and pregnancy of unknown location and progesterone as a predictor of success