Abstract:Objectives:To determine if the Nuchal Index (NIx) is increased in euploid fetuses diagnosed with an isolated structural congenital heart defect (CHD) on fetal echocardiogram. Methods: A prospective case-control study was conducted from March 2002 to July 2003. All patients between 18 and 24 weeks' gestation referred for fetal echocardiography were approached for participation. Patients were excluded if other major anomalies or an abnormal karyotype were present. The NIx was calculated as the mean nuchal thickn… Show more
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