P0461 Disease Activity Index and Anti-CCP Titer in Rheumatoid Arthritis

Relationship Between Serum Vitamin D Level and Disease Severity in Rheumatoid Arthritis

“…Also, in Braun-Moscovici et al 37 study, 42% and in Oelzner study, 32% of patients with rheumatoid arthritis were deficient in Vitamin D. 38 Consistent with this study, Shadmanfar et al, 30 as well as Abbasi et al, 29 In line with this results, increased the severity of the disease in patients with lower serum levels of the Vitamin D; Reported. Unlike this study, in the investigation of Kavoodi et al, 20 no significant relationship was observed between serum Vitamin D levels and disease severity. Patel et al’s 34 inspection, serum Vitamin D levels were related to disease activity and every 10 ng/mL rise in Vitamin levels was accompanied by a 0.3 decrease in rheumatoid disease activity based on DAS28 and a 25% decrease in CRP.…”

“…In contrast to this study, the mean cases of the disease in the study of Shadmanfar et al 30 (12% remission, 8% weak, 62% moderate, and 18% high activity) and the study by Kavoodi et al (5.2% high, 50.4% moderate (28.1% low and in 16.3% remission) was more than our study. 20 Also, contrary to this study, in Abbasi et al, 29 the severity of the disease was reported to be low by 56.2%, 21.5% moderate, and high in 22.2%, the proportion of mild cases was higher. Severe cases of the disease in this study were higher than the Salesi et al 21 (Mean DAS28 score in the studied patients was 5.5 ± 1.2).…”

“…Hovsepian et al 24 study presented the prevalence of mild, moderate, and severe Vitamin D deficiencies among the adult population was 19.6%, 23.9%, and 26.9% respectively, that was lower than our study. Also, the prevalence of Vitamin D deficiency in Asian countries among adult population was reported to be 14% to 59%, [19][20][21] that is more than Vitamin D deficiency in our research. Several studies in different parts of Iran and in different age-groups have shown the high prevalence of Vitamin D deficiency.…”

“…Consistent with this analysis, Mena et al 13 in India reported the mean serum level of the Vitamin D at 31.68 ± 14.13 with the aim of investigating the relationship between serum Vitamin D levels and disease severity in patients with rheumatoid arthritis. In Salesi et al, 20 as well as Kavoodi et al, 21 The mean serum levels of the Vitamin D were 105.61 ± 29.3 and 152.21 ± 35.92 ng/mL, respectively. These values (Vitamin D levels) were much higher than the values obtained in the current research.…”

“…In contrast to this study, the mean cases of the disease in the study of Shadmanfar et al 30 (12% remission, 8% weak, 62% moderate, and 18% high activity) and the study by Kavoodi et al (5.2% high, 50.4% moderate (28.1% low and in 16.3% remission) was more than our study. 20 …”