P0421 Human Tissue Transglutaminase Antibodies Screening by Immunochromatographic Line Immunoassay for the Early Diagnosis of Celiac Disease in Turkish Children

eken, F. Demir; Kansu, Aydan; Kulolu, Z.; riz, H. G; Girgin, Nurten

doi:10.1097/00005176-200406001-00545

Cited by 16 publications

(39 citation statements)

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“…CD is quite a prevalent autoimmune disorder in Turkey. In local studies prevalence of CD was found to be 1/158 (0.6 %) and 1/111 (0.9%) in Turkish children [16,17]. In the present study, the prevalence of biopsy-proven CD in children with AT was 5/101 (4.9%), increased by more than eightfold.…”

Section: Discussionsupporting

confidence: 48%

Prevalence of Celiac Disease in Turkish Children with Autoimmune Thyroiditis

et al. 2008

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The close association between celiac disease (CD) and autoimmune disorders is well documented in adult and pediatric patients. The aim of this study is to determine the prevalence of CD in Turkish children with autoimmune thyroiditis (AT). Sera from 101 children with AT (11 boys and 90 girls, from 2 to 18 years of age; mean age 12.28 +/- 3.26 years) and 103 healthy children (46 boys and 57 girls, from 3.5 to 17 years of age; mean age 12.18 +/- 3.11 years) were screened for CD using the IgA anti-tissue transglutaminase (IgA anti-tTG) antibody and total serum IgA. Small intestinal biopsy was offered to all antibody-positive patients. IgA anti-tTG was positive in eight children (7.9%) with AT. None of the serum samples of healthy children were positive for IgA anti-tTG antibody. Selective IgA deficiency was not detected in patients or controls. Intestinal biopsy was accepted by seven patients. In five patients (4.9%), subtotal villous atrophy was found. These findings indicate that the prevalence of CD is higher in Turkish children with AT than in healthy controls. Routine screening for CD should be performed in children with AT.

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Section: Discussionsupporting

confidence: 48%

Prevalence of Celiac Disease in Turkish Children with Autoimmune Thyroiditis

et al. 2008

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“…Thus, the pooled prevalence of CD among adults was 0.4% (95% CI 0.3%, 0.6%) . Similarly, of 29 423 children screened in six studies, 133 children were reported to have CD . Therefore, the pooled prevalence of CD amongst children from Asian countries was 0.5% (95% CI 0.3%, 0.7%) .…”

Section: Resultsmentioning

confidence: 97%

Prevalence of celiac disease in Asia: A systematic review and meta‐analysis

Singh

Arora

Singh

et al. 2016

J of Gastro and Hepatol

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“…Patolojik olarak, ince barsak mukozasında intraepitelyal lenfosit (İEL) artışı, kript hiperplazisi ve villus atrofisi bulguları izlenmektedir. 81 Çölyak hastalığı, dünyada en yaygın görülen genetik hastalıklardan biridir. Sıklığı 1/100 kadardır.…”

Section: üLseratif Kolitunclassified

Genetic Approach to Frequently Seen Pediatric Gastrointestinal System Diseases: Review

Ataman¹,

Erçal²

2016

Turkiye Klinikleri J Pediatr

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P0421 Human Tissue Transglutaminase Antibodies Screening by Immunochromatographic Line Immunoassay for the Early Diagnosis of Celiac Disease in Turkish Children

Cited by 16 publications

References 0 publications

Prevalence of Celiac Disease in Turkish Children with Autoimmune Thyroiditis

Prevalence of Celiac Disease in Turkish Children with Autoimmune Thyroiditis

Prevalence of celiac disease in Asia: A systematic review and meta‐analysis

Genetic Approach to Frequently Seen Pediatric Gastrointestinal System Diseases: Review

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