P033 Drugs used in the treatment of fistulae in Crohn's disease preserve mesenchymal stem cell survival

Human mesenchymal stromal cells can uptake and release ciprofloxacin, acquiring in vitro anti-bacterial activity

“…There is evidence that infused MSCs have higher engraftment capacity within sites of inflammation or injury (28). Furthermore, it has been demonstrated that CIP does not alter the function of human MSCs, also in association with other drugs (as metronidazole and inflitimab) (29). Significant data on active arrest of MSCs within inflamed tissues have been reported (30,31).…”