P0309 Prevalence of Hepatitis C Infection and Response of Treatment to Interferon Alpha in Beta Thalassemia Patients

Mohan, Nihar; Majumdar, Ishita; Kaul, Dinesh; Khanna, Varun

doi:10.1097/00005176-200406001-00433

Cited by 2 publications

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“…Clearly, the treatment of chronic HCV in these patients has become imperative, along with the management of iron overload. In an Indian study by Mohan et al (81) with 148 transfusion‐dependent β‐thalassemics, anti‐HCV antibodies were positive in 45.9% and HCV RNA in 20.2%. With IFN monotherapy in HCV RNA–positive patients, SVR was found to be 87.5%.…”

Section: Treatment Of Special Groupsmentioning

confidence: 96%

“…The prevalence of HCV infection in patients with thalassemia in Asia is high and varies from 20% to 64% (79,80,81). Patients are generally infected with HCV during the first 10 years of life, and persistence of HCV infection is favored by iron overload and the various immune abnormalities underlying susceptibility to infections.…”

Section: Treatment Of Special Groupsmentioning

confidence: 99%

See 1 more Smart Citation

Chronic Hepatitis C Virus Infection in Children

Mohan

González‐Peralta

Fujisawa³

et al. 2010

J. pediatr. gastroenterol. nutr.

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The importance of hepatitis C viral infection in the health care of children has grown in recent decades. More is now known about the epidemiology of this infection in children and the progression of disease in the pediatric age group, and the treatment options are increasing. In this review, we update readers on the state of our understanding of hepatitis C infection in children, provide the current recommendations for monitoring and treatment, and discuss emerging therapies.

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Section: Treatment Of Special Groupsmentioning

confidence: 96%

Section: Treatment Of Special Groupsmentioning

confidence: 99%