P03.36: Sirenomelia: a case report

First Trimester Diagnosis of Sirenomelia by 2D and 3D Ultrasound

“…It has an incidence of 1/60,000 births [7,8] and occurs 100-150 times more frequently in monozygotic twins than in singletons [9] . Stocker et al [10] proposed a new classification based on the variable degree of fusion of the femurs, tibias and fibulas.…”

Sirenomelia Associated with Truncus Arteriosus

“…Syrenomelia sequence is a rare (incidence of 1: 60000 births) [1,2] lethal pattern of congenital anomalies characterized by a number of hallmark skeletal anomalies including fusion of the lower extremities or a single lower limb, bilateral renal agenesis or dysgenesis with absent or hypoplastic renal arteries, oligohydramnios and the presence of aberrant vasculature. Prenatal sonographic detection of the lower limb anomalies associated with this condition is severely limited by the oligohydramnios that accompanies bilateral renal agenesis.…”

“…This latter association has been never described before in the revision of the literature. 100,000 live births [1,2]. It is 100 times more likely to occur in monozygotic than in dizygotic twins or singletons [11].…”