P03.03: Three cases of double aortic arch diagnosed in fetal period

Abstract

Objectives:To evaluate the diagnostic accuracy of prenatal screening for congenital heart diseases (CHD) based on the combination of the four-chamber view and the three-vessel view in an unselected population. Methods: A prospective study on 8025 scanned fetuses was performed. All singleton pregnancies scheduled for a routine prenatal ultrasound screening at 20-24 weeks' gestation and subsequently delivered within our unit were included. Data were recorded regarding visualization of the four-chamber view, the outflow tracts and the three-vessel view. Suspected CHD was confirmed by postmortem or postnatal echocardiography. We obtained the followup data of the newborns and calculated the diagnostic accuracy of the test. Results: Major CHD were identified in 32 cases (4.0‰) of which 26 cases (81.3%) were diagnosed antenatally and 6 postnatally. Four cases were false positive. Twenty-one cases were identified by the four-chamber view and five as a result of the abnormal three-vessel view. The sensitive of the four-chamber view alone was 65.6% (17/32), and the specificity was 99.9%. The sensitivity of the combination of the four-chamber view and the three-vessel view was 81.3% (26/32), and the specificity was 99.9%. Conclusions:The three-vessel view is reliable and easy methods to be used in a routine antenatal clinic, along with the four-chamber view.