P02.44: Congenital diaphragmatic hernia in a Saudi population: a 5‐year review

Sultan, Syed Farjad; Wahbi, H.

doi:10.1002/uog.3476

Cited by 1 publication

(4 citation statements)

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“…On the other hand, in Saudi Arabia, several studies reported a mortality rate ranging from 28.6% to 48%, which means that our mortality rate is higher compared to other centers in our region. Moreover, the demographics of CDH patients were closely similar to those of other studies in Saudi Arabia [12][13][14][15]. Most cases occur on the left side, with the absence of hernia sac formation and abdominal organs [15][16][17].…”

Section: Discussionsupporting

confidence: 75%

“…Moreover, the demographics of CDH patients were closely similar to those of other studies in Saudi Arabia [12][13][14][15]. Most cases occur on the left side, with the absence of hernia sac formation and abdominal organs [15][16][17].…”

Section: Discussionsupporting

confidence: 75%

“…Moreover, the demographics of CDH patients were closely similar to those of other studies in Saudi Arabia [ 12 - 15 ]. Most cases occur on the left side, with the absence of hernia sac formation and abdominal organs [ 15 - 17 ]. [MSAB1] In the literature on newborns in the United States, the highest prevalence of CDH is in the western region.…”

Section: Discussionsupporting

confidence: 74%

“…The remaining 22 infants (48.8%) (19 males, three females) survived. The median length of stay for infants who survived was 18(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) days. The mean age of mothers whose infants died was 30.23 (5.88±), and a mean of 28.18 (6.12±) for those whose infants survived.…”

mentioning

confidence: 99%

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Survival and Predictors of Mortality of Congenital Diaphragmatic Hernia in Newborns at a Tertiary Care Hospital in Saudi Arabia

Al-Shareef,

Bhader,

Alhindi

et al. 2024

Cureus

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Background Congenital diaphragmatic hernia (CDH) is a condition where abdominal contents protrude into the chest due to defects in the diaphragm muscle. It is considered an emergency that needs urgent intervention to prevent further complications or death. Our study aimed to estimate survival and evaluate predictors of mortality in newborns with CDH using available prediction tools in the literature. Methods This retrospective cohort study included neonates with CDH in King Abdulaziz Medical City (KAMC), Jeddah, from 2000 to 2021. Prevalence, demographics, and clinical characteristics were compared between surviving and deceased infants. C-statistics were used to measure the area under the curve for the prenatal and postnatal predictor tools, and a p-value of <0.05 was considered significant. Results Between 2000 and 2021, 45 neonates with CDH were included (six per 10,000 inborn live births). The mortality rate was 51.1%. The differences in demographics were not significant among surviving and deceased patients. One prenatal predictor tool, the lung-to-head ratio, was found to be significant; in addition, three postnatal predictor tools of mortality, SNAP-II, CDHSG-probability survival, and Brindle Score, had the highest concordance (C) statistics of 0.8, 0.79, and 0.8, respectively. Conclusion Although the incidence of CDH was found to be higher in our study compared to global statistics, our mortality rates correspond with international figures. The most significant differences between predictors and prediction models of mortality were lung-to-head ratio prenatally, SNAP-II, CDHSG-probability survival, and Brindle Score postnatally. Further multicentered studies are recommended with a larger sample size.

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