P017 Leukocytoclastic vasculitis: Clinic, immunologic, epidemiologic study of 70 patients

Papi, Massimo; Ruggeri, Salvatore; Depita, O; Corona, Rachel; Silvestri, Luciano; Didona, Biagio; Chinni, L. M.

doi:10.1016/s0926-9959(97)89492-5

Cited by 2 publications

(1 citation statement)

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“…CLV is essentially a histopathological term and includes a heterogeneous group of small vessel vasculitis that may be a primary disorder or a clinical aspect of systemic vasculitis. A number of associated factors have been reported, some of them being strongly suspected to play an etiological role such as concomitant viral, microbial and mycotic infections, drug intake, CTDs, and malignancies 12,13 (Table 4). More than 50% of the patients do not present apparent association.…”

Section: Clinical Aspects Of the Main Cutaneous Vasculitis Associatedmentioning

confidence: 99%

Vasculitic Ulcers

Papi

2015

The International Journal of Lower Extremity Wounds

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Vasculitic ulcers are an emerging problem in wound care that needs to be well defined and adequately approached by caregivers. Cutaneous vasculitis includes several inflammatory disorders that compromise microvessels and specifically the cutaneous vascular system: arterioles, capillaries, postcapillary venules. The pathogenetic role of circulating immunocomplexes and autoantibodies (antineutrophil antibodies) in these diseases has been widely demonstrated in animal models and in humans. Vasculitis can be limited to the skin or represent the cutaneous signs in case of systemic vasculitis with visceral involvement. The injury of cutaneous microvessels may result in impairment of blood flow and consequent focal ischemia and formation of skin ulcers. The ulcers are often multiple and localized on the lower leg and foot where the microcirculatory anatomy and rheologic dynamics are predisposing factors. Approximately 3% to 5% of skin ulcers may be caused by a vasculitic disorder.

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Section: Clinical Aspects Of the Main Cutaneous Vasculitis Associatedmentioning

confidence: 99%