P‐Wave Duration and Dispersion in Obese Subjects

Koşar, Feridun; Aksoy, Yüksel; Ari, Fahri; Keskin, Lezzan; Şahin, İ̇brahim

doi:10.1111/j.1542-474x.2007.00194.x

Cited by 57 publications

(55 citation statements)

References 26 publications

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“…This increase in duration with increasing adiposity is consistent with prior smaller data sets, 7,10-12 and others have reported increased P wave durations and left atrial sizes by echocardiography when obese subjects were compared to age-and sex-matched controls. 10,11 It is possible the increased duration demonstrated here may be a manifestation of left atrial enlargement directly related to obesity, as secondarily associated disease states (e.g., systemic hypertension, diabetes mellitus, and coronary artery disease) are unlikely to have developed yet in this young cohort.…”

Section: Discussionmentioning

confidence: 92%

The effects of body mass index on surface electrocardiograms in young adults

Nasir

Rubal

Jones

2012

Journal of Electrocardiology

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Section: Discussionmentioning

confidence: 92%

The effects of body mass index on surface electrocardiograms in young adults

Nasir

Rubal

Jones

2012

Journal of Electrocardiology

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“…Obesity increases the risk of developing AF by 49% in the general population, and the risk escalates in parallel with increased body mass index. 36 Kosar et al 37 reported that obesity affected PWD and changes in PWD were closely related to body mass index. Left atrium size was correlated with PWD, as expected.…”

Section: Resultsmentioning

confidence: 99%

Perindopril decreases P wave dispersion in patients with stage 1 hypertension

Özben

Sumerkan

Tanrikulu

et al. 2009

J Renin Angiotensin Aldosterone Syst

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Introduction. Angiotensin-converting enzyme inhibitors prevent atrial fibrillation episodes by effective control of blood pressure and improving electrical and structural remodelling in the atria. Increased P wave dispersion (PWD) is a non-invasive electrocardiographic marker for paroxysmal atrial fibrillation. The aim of the study was to evaluate the effect of perindopril treatment on PWD in hypertensive patients. Methods. Forty-eight hypertensive patients (mean age 57.4±11.8 years, 18 men) were included. Blood pressure values were determined and 12-lead electrocardiograms were recorded at the beginning and at the first week, first month, third month and sixth month of the perindopril treatment. The difference between maximum and minimum P wave durations was calculated as PWD. Results. PWDs were significantly shortened at the first, third and sixth months (41.7±8.8 ms, 39.1±6.9 ms and 38.3±7.1 ms, respectively) compared with baseline and first-week measurements (54.3±9.2 ms and 49.0±9.1 ms, respectively, p<0.001). Baseline PWD was correlated with body mass index (r=0.32, p=0.026), while PWD at the sixth month of treatment was significantly correlated with left atrial volume index (r=0.30, p=0.042). Multiple linear regression analysis revealed that PWD at the sixth month was related to baseline PWD (p=0.001). Conclusion. Perindopril treatment significantly reduced PWD in hypertensive patients.

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“…P-wave dispersion is thought to reflect 'discontinuous and inhomogeneous propagation of sinus impulses and prolongation of atrial conduction time' [18].…”

Section: Mechanisms Of How Obesity and Obstructive Sleep Apnea Increamentioning

confidence: 99%