P mutants with different promoting period and their application for quorum sensing regulated protein expression

Quorum Sensing as a Trigger That Improves Characteristics of Microbial Biocatalysts

“…The effect of QS induced by specific molecules of Gram-negative bacteria, N -acyl homoserine lactones (AHL), on the physicochemical properties of ANAMMOX granulated sludge [ 12 , 13 , 14 , 15 , 16 ] has been actively studied in recent years ( Table 1 ) [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ].…”

“…E. coli cells are most often used as host cells for the production of a number of products due to the presence of thoroughly studied metabolic pathways, engineering tools, and the ease of culturing highly concentrated populations [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. In studies [ 17 , 19 , 21 , 23 ], synthetic microbial biocatalysts were developed and constructed using components of the Lux-type QS system in genetic circuits to regulate metabolic pathways for the biosynthesis of isopropanol, salicylic acid, 4-hydroxycoumarin, bisabolene, alginate lyase, and esterase. A modified version of the QS-MTS (metabolic toggle switch) system to stabilize the efficiency of QS signaling and regulation of metabolism was constructed in E. coli cells to increase the production of pyruvate and acetate [ 25 ].…”

“…Lux [23] A self-induced dynamic regulated expression (SIDRE) for metabolic control Alginate lyase and Esterase…”

“…E. coli cells are most often used as host cells for the production of a number of products due to the presence of thoroughly studied metabolic pathways, engineering tools, and the ease of culturing highly concentrated populations [17][18][19][20][21][22][23][24][25]. In studies [17,19,21,23], synthetic microbial biocatalysts were developed and constructed using components of the Luxtype QS system in genetic circuits to regulate metabolic pathways for the biosynthesis of isopropanol, salicylic acid, 4-hydroxycoumarin, bisabolene, alginate lyase, and esterase.…”

“…As the recent studies of various BCs have shown, the transition of cells from the normal state into the state of QS can be caused by the use of different approaches ( Figure 1 ) [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ]. The summation of these approaches and the analysis of their effectiveness have undoubted scientific and practical significance, and therefore have become the object of attention of this review.…”