P/M Forging Successes

Ashley, Alan

doi:10.4271/770099

Cited by 4 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The present results and those of others suggest the need for a collaboration between T cells and macrophages in the mediation of nonspecific tumor growth inhibition. Both Ashley et al [21] and Tuttle and North [13] showed a similar need for radiation-sensitive cells in recipient mice, as we have shown here for the chicken, and both groups proposed activation of macrophages (monocytes) as the effector mechanism. Preliminary results obtained in our laboratory indeed suggest that macrophages activated in vitro and injected with tumor cells into wing webs of recipients, can by themselves cause tumor growth inhibition ( Concomitant immunity to unrelated tumors in tumor-bearing mice has been noted by North and Kirstein [28] and may well depend on a generalized activation of macrophages in such mice bearing progressively growing tumor, as was indicated by the presence of enhanced resistance t o Listeria monocytogenes infection.…”

Section: Discussionsupporting

confidence: 82%

Immunity to transplantable carcinogen‐induced fibrosarcomas in B2/B2 chickens. III. Tumor growth inhibition by local delayed hypersensitivity reactions to unrelated antigens

Palladino

Thorbecke

1978

Eur J Immunol

View full text Add to dashboard Cite

Delayed hypersensitivity (DH) reaction to human Ig, corynebacterium parvum or allogeneic cells at the site of tumor cell injection, suppressed the fibrosarcoma (SCFS) growth in chickens. Spleen cells of SC chickens sensitized to human Ig or C. parvum suppressed SCFS growth when adoptively transferred with tumor cells, but only when the sensitizing antigen was present locally. This suppression did not occur in irradiated recipients, SCFS I cells injected into wattles of chickens immune to the tumor, provoked a local DH reaction. Spleen cells from donors sensitized to SCFS I adoptively transferred immunity to both SCFS I and SCFS II when cells of the two tumors were mixed together before injection, but not when SCFS II cells were injected alone. Tumor-specific and nontumor-specific DH may be essential for local suppression of fibrosarcoma growth in chickens.

show abstract

Section: Discussionsupporting

confidence: 82%

Immunity to transplantable carcinogen‐induced fibrosarcomas in B2/B2 chickens. III. Tumor growth inhibition by local delayed hypersensitivity reactions to unrelated antigens

Palladino

Thorbecke

1978

Eur J Immunol

View full text Add to dashboard Cite

show abstract

“…The formation of the skarn at Gumble appears to have followed the paths proposed by Atkinson and Einaudi (1978), and Verkaeran and Bartholome (1979), and to some extent, that described by Kwak and Tan (1981), and Ashley (1980). The primary stage involves the alteration of limestone to hedenbergite, andradite, grossular, epidote, idocrase, diopside, wollastonite, and magnetite.…”

mentioning

confidence: 55%

Malayaite and tin-bearing garnet from a skarn at Gumble, NSW, Australia

Mulholland

1984

Mineral. mag.

View full text Add to dashboard Cite

Malayaite and tin-bearing garnet occur within a skarn assemblage at Gumble, NSW. A metasomatic origin is proposed for these minerals under conditions of T = 300-500°C Xco2 < 0.30 and fO2 = 10−18 to 10−30 bars. Malayaite has formed as a result of reaction between a metasomatic fluid rich in Sn, F, H2O and silica, and tin-bearing andradite and wollastonite. The main requirements for tin-bearing skarn formation appear to be an F-Sn-rich granite, an iron-rich skarn assemblage, and a relatively long cooling history.

show abstract

“…We do not know whether the Ag characterized in the present study are related to any of the protective Ag of Salmonellae that have been deseribed by others, although the method of preparing the slIRX whieh we used as starting tnaterial for purification (19) makes it unlikely that API6 is an outer membrane protein. The'T cell western blot' method used to monitor antigenic activity has the advantage that Ag do not have to be preselected (e.g.…”

Section: Discussionmentioning

confidence: 87%

Partial purification and characterization of low molecular weight antigens of Salmonella enteritidis 11RX

Vordermeier

Kotlarski²

1990

Immunology & Cell Biology

View full text Add to dashboard Cite

Summary Sephadcx GlOO chromatography and preparative sodium dodeLylsulfate-polyacrylamldc gel elcclrophorosis(SDS-P,'\GE) using \6% polyacrylamide gels were used for the partial purification of 16-18 kDa proteins able to stimulate Salmonella cutcritulis llRX-priinud T cells of (BALB/cXC57BL/6J)Fl mice. . A soluble antigen (Ag)extract of S, cmmV/ffo 1 IRX (sl I RX) was used as the starting material for purification for two reasons. First, sl IRX had been previously shown lo induce in viira proliferation of Salnwiiclln-primcd T cells; second, initial analysis of SDS-P,\GE fractionated sl IRX Ag using the 'T eell western blot" technique indicated that T cell stimulatory activity was located only in Ihe 16-18 kDa region. The partially purified antigens were able to elicit delayed-type hypersensitivity reactions//) Wio, and stimulated in I77»Y> proliferation and interleukin-2 release from 1 IRX-primod T cells and Tceil lines and clones derived from these cells, indicating that they are major antigenic determinants of 5. enteritidis I IRX.Testingof l6-18kDa proteins of several other bacteria indicated that these antigens maybe "common" and expressed by a number of organisms belonging to the Enterohaeteriacae.

show abstract

P/M Forging Successes

Cited by 4 publications

References 2 publications

Immunity to transplantable carcinogen‐induced fibrosarcomas in B2/B2 chickens. III. Tumor growth inhibition by local delayed hypersensitivity reactions to unrelated antigens

Immunity to transplantable carcinogen‐induced fibrosarcomas in B2/B2 chickens. III. Tumor growth inhibition by local delayed hypersensitivity reactions to unrelated antigens

Malayaite and tin-bearing garnet from a skarn at Gumble, NSW, Australia

Partial purification and characterization of low molecular weight antigens of Salmonella enteritidis 11RX

Contact Info

Product

Resources

About