P.470 Prevalence of hepatitis B antibodies in health-care workers in Yasuj/Iran hospitals

Sarkari, B.; Zargar, Mahrukh Hameed; Mohammadi, Raheleh; Askarian, S.

doi:10.1016/s1386-6532(06)80643-8

Cited by 4 publications

(8 citation statements)

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“…Reports of the Center for Diseases Control and Prevention[ 23 ] and American Academy of Pediatrics Infectious Diseases[ 24 ] showed that three times infusion of HBV vaccine caused the occurrence of protective antibody in 85%–100% of people which was higher than our report. The levels of immunity against vaccination with recombinant hepatitis B vaccine in a study which was conducted in Yemen[ 25 ] and those of Iran[ 26 27 28 ] had ranges of 50%–80% which was higher than our findings. Several studies have been reported that immune response to hepatitis B vaccine is depended on host factors such as sex, age, weight, genetics, and immunocompetent of individuals.…”

Section: Discussioncontrasting

confidence: 92%

Evaluation of response to hepatitis B vaccine in iranian 6–18-year-old students

Jouneghani

Chaleshtori

Khoshdel³

et al. 2017

J Res Med Sci

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Background:Hepatitis B is a dangerous disease with high morbidity and mortality rates all around the world. Vaccination is the most important way to its prevention and control. This cross-sectional study was carried out to study the levels of immunogenicity to hepatitis B vaccine in students.Materials and Methods:Six hundred and forty-four students aged 6–18 years including 316 girls and 328 boys were selected from the Chaharmahal Va Bakhtiari province. Selected students had been received three doses of recombinant vaccine (0, 1, and 6 months). Blood samples were taken and the titers of hepatitis B surface antigen were studied.Results:From a total of 644 students, 396 (61.5%) had a titer lesser than 10 mIu/ml and 248 (38.5%) had a titer higher than 10 mIu/ml. Therefore, the level of respond to vaccine with 95% confidence was 38.5% (34.7%–42.4%). Levels of respond to vaccine were related to age, body mass index (BMI), and educational level and were not related to sex and habit of students.Conclusion:Reverse significant relation was seen between the respond to vaccine and age and BMI in a way which the titers of antibody were lower in students with higher age and BMI.

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Section: Discussioncontrasting

confidence: 92%

Evaluation of response to hepatitis B vaccine in iranian 6–18-year-old students

Jouneghani

Chaleshtori

Khoshdel³

et al. 2017

J Res Med Sci

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“…Results of two studies on health care workers and one study on medical students about immunization of HBV Vaccine in Yasuj, Shahrekord and Rasht cities of Iran respectively, showed that females had higher titer than male (Sarkari et al, 2007;Parmar et al, 2011;Ghanaei et al, 2006). Martinez et al (1998) study showed that increasing BMI is a risk factor for lesser response to HBV Vaccine.…”

Section: Discussionmentioning

confidence: 99%

Immunity Level to Hepatitis B Virus in Vaccinated Medical Students

Jahromi¹

2013

OnLine Journal of Biological Sciences

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Hepatitis B is a wide world disease and more than 1/3 of people in the world are HBs Ag positive. HBV causes chronic hepatitis, acute hepatitis, chronic cirrhosis and hepatocellular carcinoma in adults and children. This research was done for evaluation of immunogenicity of HBV vaccine with HBs Ab measurement after vaccination. This descriptive cross-sectional study was done on 135 medical students of Jahrom University of medical science who had been vaccinated three times. The obtained serum was tested by Elisa method to determine for Anti-HBs antibodies. All collected data were entered in statistical software program SPSS (version 16) and were analyzed by descriptive statistics and chi-square and t-test. Out of 135 medical students, 102(75.6%) were women. In this study 13(9.6%) subjects had anti-HBs titer of 10-100(mIu mL −1 ) and 122(90.4%) subjects had anti-HBs titer of >100 mIu mL −1 . There was no correlation between immunity level and age, sex, BMI, time after last vaccination and past record of needle stick at work place. Although immunity to hepatitis B was in protective level among all participants, assessment of immunity in healthcare workers after complete vaccination recommended.

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“…Among the remainder 106 articles, 36 ones were excluded due to inconsistency with the criteria of the current study, and 6 other studies were excluded due to unavailability of the fulltext article or required data. From 64 accepted articles, 14 articles had been performed on children under 10 years old,[ 51 52 53 54 55 56 57 58 59 60 61 62 63 64 ] 38 articles on adults (more than 18 years old),[ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 ] and 12 on individuals with a specific disease (thalassemia, acquired immunodeficiency syndrome [AIDS], hemodialysis)[ 64 65 66 67 68 69 70 71 72 73 74 75 ] [ Figure 1 ].…”

Section: Methodsmentioning

confidence: 99%

“…From 64 accepted articles, 14 articles had been performed on children under 10-year-old,[ 51 52 53 54 55 56 57 58 59 60 61 62 63 64 ] 38 articles on adults (more than 18-year-old),[ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 ] and 12 on individuals with a specific disease (thalassemia, AIDS, hemodialysis). [ 64 65 66 67 68 69 70 71 72 73 74 75 ] 39 studies have assessed the efficacy of the vaccine on both genders (separately and in combination).…”

Section: Methodsmentioning

confidence: 99%

“…Studies in Iran and other parts of the world have reported an immunizing rate of 71-95% for this vaccine. [ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 , 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 ] Studies have shown that various factors may affect the efficacy of hepatitis B vaccine including vaccine type, times of vaccination,[ 76 ] genetic background,[ 77 ] age,[ 78 ] weight, smoking, and alcohol consumption. [ 79 ]…”

Section: Introductionmentioning

confidence: 99%

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