P-360 EGFR-inhibitors in metastatic wild-type RAS colorectal cancer: Experience of the oncology department of Mohammed VI University Hospital in Marrakech

Abstract

and blood group A was firstly discovered by Aird et al. The study aims to evaluate the cancer distributions and prognostic significance for the HER2 positive gastric cancer.Methods: The data of 112 patients were retrospectively reviewed. The ABO blood groups, clinical, and histopathological data of the patients were recorded. The ABO blood group distributions of the patients were compared to healthy donors (n:130,909) by chi-square test.Results: The median follow-up period was 15.5 months (range: 1.07-81.1 months). The percentages of female and male patients were 29% and 71%, retrospectively. The median age at diagnosis was 61 years (range: 24-91 years). The median OS was 17.9AE2.3 months (13.2-22.5 months). Overall distributions of ABO blood groups were different between patients (57.1% A, 10.7% B, 6.3% AB, 25.9% O) and controls (41.87% A, 15.29% B, 7.91% AB, 34.93% O) (p¼0.013). The distribution of Rh factor was comparable between patients and the control group (p¼0.074). In univariate analysis, ABO blood groups were not a prognostic factor on OS. Conclusion:In this study, we determined to the A blood frequency in HER2 positive gastric cancer is more common than other blood groups. 0 blood groups may be protective for HER2 positive gastric cancer.Legal entity responsible for the study: The authors.