P-223 The Association of Hypertensive Left Ventricular Hypertrophy and Risk of Cardiovascular Disease and Death in a Cohort Study in Beijing

Prognostic value of left ventricular hypertrophy in hypertensive patients: A meta‐analysis of electrocardiographic studies

“…Five studies reported the association between electrocardiographic LVH and major adverse cardiovascular events. Comparison with those with and without LVH patients (Figure ), the pooled RR was 1.53 (95% CI 1.27‐1.86; I 2 = 26.3%; P = .254) for Sokolow‐Lyon voltage criteria and 1.46 (95% CI 1.22‐1.76; I 2 = 17.7%; P = .302) for Cornell voltage criteria . The pooled RR after removing one study at a time ranged from 1.40 to 1.63 for Sokolow‐Lyon voltage and 1.39‐1.51 for Cornell voltage.…”

“…Of which, 40 articles were removed for various reasons. Thus, nine studies involving 41 870 hypertensive patients satisfied our inclusion criteria.…”

“…Six studies reported the association between electrocardiographic LVH and all‐cause mortality. Comparison with those with and without LVH patients (Figure ), the pooled RR was 1.30 (95% CI 1.01‐1.66; I 2 = 33.0%; P = .214) for Sokolow‐Lyon voltage criteria, 1.33 (95% CI 1.20‐1.47; I 2 = 0.0%; P = .467) for Cornell voltage criteria and 1.31 (95% CI 0.97‐1.78; I 2 = 51.8%; P = .150) for Cornell product criteria . In the sensitivity analyses, the pooled RR after removing one study at a time ranged from 1.15 to 1.50 and the low 95% CI ranged from 0.86 to 1.07 for Sokolow‐Lyon voltage.…”

“…Six studies 7,[10][11][12]17,18 reported the association between electrocardiographic LVH and all-cause mortality. Comparison with those with and without LVH patients (Figure 2), the pooled RR was 1.30 (95% CI 1.01-1.66; I 2 = 33.0%; P = .214) for Sokolow-Lyon voltage criteria, 7,12,17 1.33 (95% CI 1.20-1.47; I 2 = 0.0%; P = .467) for Cornell voltage criteria 10-12,17 and 1.31 (95% CI 0.97-1.78; I 2 = 51.8%; P = .150) for Cornell product criteria.…”

“…5 The Sokolow-Lyon, Cornell voltage, and Cornell product are the most frequently applied the electrocardiographic criteria for diagnosis of LVH. 6 Several studies [7][8][9][10][11] have been reported that electrocardiographic LVH could help clinicians to improve risk stratification of hypertensive patients. However, the prognostic values of LVH determined by different electrocardiographic criteria are controversial in this specific population.…”