P-19 Double follicular aspiration can save an IVF cycle after improper administration of hCG

Esposito, Melissa; Schäfer, Dieter; Bucci, J.; Bunso, S.; Coutifaris, Christos; Patrizio, Pasquale

doi:10.1016/s0015-0282(99)00055-2

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found no evidence of any relationship between follicular antioxidant activity and the presence of oocytes in follicular uid, both with baseline TAC and antioxidant consumption (two-point assay). The factors responsible for non-recovery of oocytes from follicles are not clear but there is some evidence that this may be related to oocyte immaturity, possibly secondary to low HCG levels, an underlying ovulatory disorder or premature oocyte atresia (Awonuga et al, 1998;Esposito and Patrizio, 2000). It is therefore of interest that levels of glutathione, which is thought to be the main non-enzymatic defence system against the effects of oxygen radicals on oocytes and embryos (Takahashi et al, 1993;Gardiner et al, 1998), are higher in mature compared with immature hamster oocytes (Gwatkin and Haidri, 1974;Perreault et al, 1988).…”

Section: Discussionmentioning

confidence: 99%

Antioxidants and reactive oxygen species in follicular fluid of women undergoing IVF: relationship to outcome

Oyawoye

Gadir²,

Garner³

et al. 2003

Human Reproduction

191

139

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Antioxidants and reactive oxygen species in follicular fluid of women undergoing IVF: relationship to outcome

Oyawoye

Gadir²,

Garner³

et al. 2003

Human Reproduction

191

139

View full text Add to dashboard Cite

show abstract

“…Since in most EFS cases, down-regulation was achieved by GnRH agonist (possibly presenting the higher prevalence of agonist over antagonist in ART cycles), shifting from an agonist to antagonist protocol was suggested (Krishna et al, 2008). In cases where no oocytes are aspirated from one ovary and hCG levels are low, some have suggested readministering hCG from a different batch and aspirating the second ovary (Khalaf and Braude, 1997;Ndukwe et al, 1997;Awonuga et al, 1998;Quintans et al, 1998;Evbuomwan et al, 1999;Esposito and Patrizio, 2000;Papier et al, 2000;Reichman et al, 2010) or even reaspirating the same follicles (Meniru and Craft, 1997;Hassan et al, 1998;Snaifer et al, 2008). Others suggested changing the hCG from a urinary to a recombinant preparation (Peñarrubia et al, 1999).…”

Section: Therapeutic Approachmentioning

confidence: 99%

Empty follicle syndrome: successful treatment in a recurrent case and review of the literature

et al. 2012

View full text Add to dashboard Cite

Empty follicle syndrome is a condition in which no oocytes are retrieved after an apparently adequate ovarian response to stimulation and meticulous follicular aspiration. It is a rare condition of obscure etiology. A patient with primary infertility who underwent seven assisted reproductive technique cycles is described. In spite of a satisfactory ovarian response, aspiration yielded no oocytes in four cycles and 1-4 low quality oocytes in three cycles. In the index treatment cycle, ovulation was triggered using GnRH agonist 40 h prior to ovum pickup and hCG was added 6 h after the first trigger. Eighteen oocytes were recovered, of which 16 were mature and were inseminated by ICSI. Two embryos were transferred 48 h after aspiration and nine embryos were cryopreserved. The patient conceived and delivered a healthy boy at 38 weeks of gestation. The literature is reviewed and possible etiologies and treatment options of this enigmatic syndrome are suggested.

show abstract

“…Zegers-Hochschild et al (8) described a series of 6 consecutive EFS cases within a 48 hour period caused by accelerated metabolism and clearance of a pharmaceutical preparation of hCG. In addition, other reports have described patient and provider errors in administration of hCG during ART (4, 10–11). Common mistakes include failure to give the injection, improper timing of the injection, or improper re-suspension of hCG solute into solution.…”

Section: Introductionmentioning

confidence: 99%

The prevalence of genuine empty follicle syndrome

Mesen

Richter

et al. 2011

Fertility and Sterility

View full text Add to dashboard Cite

Objective To describe the prevalence of “genuine” empty follicle syndrome and “false” empty follicle syndrome at ART. Design Retrospective cohort. Setting Large private fertility center. Patient(s) 12,359 patients who underwent ART between 2004 and 2009. Intervention(s) None. Main Outcome Measure(s) The failure to recover an oocyte during oocyte retrieval at ART, with and without a detectable serum β-hCG on day of retrieval. Result(s) Two cases of genuine empty follicle syndrome and 9 cases of false empty follicle syndrome were identified in the cohort examined. The prevalence of genuine empty follicle syndrome was 0.016% and the prevalence of false empty follicle syndrome was 0.072%. Only 2 out of 11 cases of EFS were considered genuine. Conclusion Genuine empty follicle syndrome is a rare occurrence. Because this syndrome tends to recur with dismal pregnancy rates at ART, continued identification and further investigation of the syndrome is needed.

show abstract

P-19 Double follicular aspiration can save an IVF cycle after improper administration of hCG

Cited by 3 publications

References 0 publications

Antioxidants and reactive oxygen species in follicular fluid of women undergoing IVF: relationship to outcome

Antioxidants and reactive oxygen species in follicular fluid of women undergoing IVF: relationship to outcome

Empty follicle syndrome: successful treatment in a recurrent case and review of the literature

The prevalence of genuine empty follicle syndrome

Contact Info

Product

Resources

About