P‐10.10: Wearable Transdermal Drug Delivery Devices based on Piezoelectric Micropumps Integrated with Microneedles Array

Abstract

Transdermal drug delivery refers to a drug delivery route that delivers drugs through the skin to produce local or systemic therapeutic effects. In this work, we propose a parallel valveless piezoelectric micropump integrated with hollow microneedle array, which can be used in flexible wearable transdermal drug delivery systems. The device consists of two valveless piezoelectric micropump, a hollow microneedle array and an electrical control module. The main structure of micropump and the hollow microneedle array are fabricated using 3D printing technology. The valveless piezoelectric micropump adopts a parallel dualpump structure with asynchronous drive, which achieves a full forward flow at the outlet and reduces the influence of backflow on the stability of the system. In addition, the parallel dual‐pump structure proposed in this work can be extended to a multimicropump parallel structure. We hope to fabricate small‐size micropump arrays on flexible substrates and integrate them into flexible wearable transdermal drug delivery systems.