P-022 Use of Seprafilm Adhesion Barrier® in Complex Large Incisional Hernia

Abstract

Aim The short-term results of the use of seprafilm® as a reinforcement of the peritoneum are presented. Material and Methods Seprafilm® was used in 5 patients with large midline and lateral incisional hernia in which Transversus Abdominis Release Technique was performed in which it was necessary to explant mesh previously. This weakness of the peritoneum was reinforced with the seprafilm® plates, to isolate the intra-abdominal contents from the mesh. Results The patients treated had an average stay of 6.6 days. All of them carried drains. There were no infectious complications in surgical site. There were no prolonged pain. All of them began tolerance the day after the surgery. At one month of the surgical intervention, there were no signs of infection, seroma or higher pain than 3 on the EVA scale. Discussion Post-operative adhesions to mesh are related to intestinal fistulas. The use of preperitoneal space to place the mesh is a good option, although sometimes it can have continuity problems, especially when there are explants of previous materials. The use of barrier materials is appropriate in these cases. Conclusion The use of Seprafilm® can be a good option as a barrier between viscera and prostheses for the prevention of adhesions.

Cyclical endometrial repair and regeneration: Molecular mechanisms, diseases, and therapeutic interventions

“…Partial investigations indicate that membrane-like barriers can promote wound repair and decrease adhesion formation by maintaining separation of the wound surface during the initial 5−7 days necessary for reepithelialization. 434,435 Several biomaterial-based tissuerepairing films, such as Seprafilm and Interceed, 249,436 have been developed. As an alternative to bioactive materials, barrier materials are receiving growing attention in the medical field.…”