2018
DOI: 10.4081/ozone.2018.7510
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Ozone therapy in painful lipodystrophies. A preliminary study

Abstract: The study focuses on lipomas, which are quite common, occur in one person out of every thousand and generally arise individually, although about 20% of those who suffer from them may have multiple cases. Ozone oxygen therapy has been shown to be effective and free of adverse side effects in all treated patients, and there are no contraindications to the use of the therapy. In most patients, the lipoma shrinks completely. The oxygen-ozone procedure is a scientifically approved and highly effective treatment for… Show more

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Cited by 4 publications
(4 citation statements)
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“…Embora faltem estudos randomizados sobre ozonioterapia no tratamento de lipomas, uma pesquisa com 20 pacientes que tinham lipomas dolorosos demonstrou que as injeções de oxigênio-ozônio reduziram em média 4 centímetros o tamanho dos lipomas e a intensidade da dor (pontuação média da escala visual analógica diminuiu de 7 para 1) em 10 sessões 18 .…”
Section: Resultsunclassified
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“…Embora faltem estudos randomizados sobre ozonioterapia no tratamento de lipomas, uma pesquisa com 20 pacientes que tinham lipomas dolorosos demonstrou que as injeções de oxigênio-ozônio reduziram em média 4 centímetros o tamanho dos lipomas e a intensidade da dor (pontuação média da escala visual analógica diminuiu de 7 para 1) em 10 sessões 18 .…”
Section: Resultsunclassified
“…A ozonioterapia é cientificamente aprovada e é um tratamento altamente eficaz para lipodistrofia 6 . Esta eficácia é alcançada porque o oxigênio-ozônio exerce sua ação por meio de três mecanismos principais: i) quebra de ácidos graxos longos em cadeias curtas e, portanto, hidrofílicas; facilitando o transporte desses pelos fluidos corporais e, permitindo, sua eliminação pelo organismo; (ii) facilita a remoção de líquidos intersticiais estagnados (edema); (iii) o oxigênio-ozônio se liga à membrana dos glóbulos vermelhos, entregando mais oxigênio aos tecidos e, portanto, ativando o metabolismo local e melhorando a circulação venosa e linfática 18 .…”
Section: Resultsunclassified
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“…Ozone-oxygen therapy can be an effective treatment for lipodystrophies through splitting fatty acids by reducing the chains and making them hydrophilic, the removal of interstitial edema due to cellulite or poor circulation, and also through providing more oxygen which improves local metabolism and venous/lymphatic circulation 5. Although randomized controlled studies are lacking, in a recent case series of 20 patients with painful lipomas, oxygen-ozone injections reduced the size of lipoma (with a mean reduction of 4 cm) and pain severity (mean visual analogue scale score decreased from 7 to 1) in 10 sessions 5. In that study, accurate diagnoses of patients’ lesions were performed using ultrasound and/or magnetic resonance imaging; however, the size of the lipomas was measured externally with palpation.…”
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confidence: 99%