“…Although ozone has been readily applied for the inactivation of different viruses [44] , [146] , [167] for a very long time, this section mainly focuses on the findings of studies that utilised ozone to inactivate the novel SARS-CoV-2 virus, while briefly highlighting key studies that applied ozone to inactivate SARS-CoV-1. It is worth mentioning that the handling of SARS-CoV-2 requires biosafety level 3 facilities; thus some studies [149] , [168] , [169] , [170] have employed biosafe substitutes/surrogates, with similar form, structure and function to the SARS-CoV-2 virus.…”