Oxytocin Secretion and Management of Parturition in the Pig

Gilbert, C.

doi:10.1111/j.1439-0531.1999.tb01240.x

Cited by 26 publications

(15 citation statements)

References 66 publications

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“…When this occurs, the piglets will be pushed against a closed cervix, which is clearly not desirable. When PG is used, the time of complete relaxation of the cervix (= the time when OT may be used) is not exactly known, and may differ between sows (Gilbert, 1999). Median of farrowing duration (184 minutes), birth interval (14 minutes) and percentage stillborn piglets (5.6 per cent) were lower compared to literature data (Oliviero and others 2009, De Pasille and Rushen, 1989).…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of different farrowing induction protocols in sows using alphaprostol on day 114 of gestation

Decaluwé

Janssens

Englebienne³

et al. 2014

Veterinary Record

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Farrowing induction in sows is frequently applied and different protocols were described. Most studies induce farrowing between day 111 and 113 of gestation, but hardly any later during gestation. The aim of this study was to investigate the effects of different induction protocols when applied on d114 of gestation. We randomly assigned 118 sows to four treatment groups: single injection of prostaglandin (1×PG), prostaglandin combined with oxytocin 24 hours later (PG+OT), half the dosage of prostaglandin twice with six hours interval (2×1/2PG), and a control group of which farrowing wasn't induced. All injections were administered intramuscularly in the neck on day 114 of gestation. A significantly higher percentage of sows started farrowing between 22 and 32 hours after induction in the PG+OT-group (68 per cent) and the 2×1/2PG-group (52 per cent) compared to the control group (23 per cent). The 1×PG-group (46 per cent) tended to differ from the control group (P=0.087). More sows from the PG+OT-group were constipated at farrowing (P=0.042). Farrowing duration, birth interval, per cent stillborn piglets, dystocia and other variables were similar between the groups. In the present herd and with continuous farrowing supervision, applying PG+OT or 2×1/2PG on d114 of gestation was efficient to induce onset of farrowing in most of the sows 22-32 hours after induction without considerable negative effects.

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Section: Discussionmentioning

confidence: 99%

Effectiveness of different farrowing induction protocols in sows using alphaprostol on day 114 of gestation

Decaluwé

Janssens

Englebienne³

et al. 2014

Veterinary Record

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“…Other studies showed no negative effects of oxytocin (10 -30IU) on these parameters (Kirkwood et al, 1998;Wehrend et al, 2005;Kaeoket et al, 2006). This may by explained by differences in time needed for a full relaxation of the cervix after the induction with prostaglandins (Gilbert et al, 1999). The administration of high doses of oxytocin may induce hard pressure upon the piglets and their umbilical cord, which leads to hypoxia (Mota-Rojas et al, 2005).…”

Section: The Use Of Oxytocin In Combination With Prostaglandinmentioning

confidence: 91%

“…In this way, the piglets will be pushed against a closed cervix, which is clearly not desirable. When prostaglandins are used, the time of complete relaxation of the cervix (= the time when oxytocin may be used) is not exactly known and may differ between sows (Gilbert et al, 1999). Some authors concluded that oxytocin (10 -30IU) increases the percentage of stillborn piglets (Yang et al, 1996;Alexopoulos et al, 1998;Cassar et al, 2005).…”

Section: The Use Of Oxytocin In Combination With Prostaglandinmentioning

confidence: 99%

“…The administration of high doses of oxytocin may induce hard pressure upon the piglets and their umbilical cord, which leads to hypoxia (Mota-Rojas et al, 2005). It may also lead to fatigue of the uterus and a decreased reaction on physiological concentrations of oxytocin (Gilbert et al, 1999). The contradictory results concerning optimal timing and dosage of oxytocin warrants further research.…”

Section: The Use Of Oxytocin In Combination With Prostaglandinmentioning

confidence: 99%

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Partusinductie bij de zeug

Decaluwé¹,

Janssens²,

Declerck³

et al. 2012

Vlaams Diergeneeskundig Tijdschrift

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Inducing parturition in the sow can be used to improve farrowing supervision, which may lead to more weaned piglets. However, if not applied properly, it may lead to premature delivery. Therefore, induction of parturition should be performed not earlier than two days before the average gestation length of the sows of a farm. To induce parturition, different protocols, such as single administration of prostaglandins, double administration of prostaglandin with 6-hour interval (split-dose technique) and a combination of prostaglandins and oxytocin 24 hours later, and different administration routes, such as intramuscular injection in the neck region and injection in the vulvar region, can be used. Other strategies exist but they are less effective and/or less frequently used. A single injection of prostaglandins results in 60% of the sows farrowing within working hours (22-32 hours after injection). Using the split-dose technique or the combination of prostaglandins and oxytocin 24 hours later, the percentage increases with 20%. The use of oxytocin however increases the risk of asphyxia in the piglets, especially in case of inappropriate use. Whether farrowing induction should be applied and which protocol used depend on the herd and the preferences of the farmer.

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“…In experiment 2, we studied the behaviour of indomethacin-treated, non-pregnant, nonnest building female pigs to examine the specificity of the changes to nest building observed in experiment 1. Preliminary data from experiment 1 on OT secretion immediately before birth have been reported elsewhere (Gilbert 1999).…”

Section: Introductionmentioning

confidence: 99%

Indomethacin blocks pre-partum nest building behaviour in the pig (Sus scrofa): effects on plasma prostaglandin F metabolite, oxytocin, cortisol and progesterone

Gilbert

Goode²,

Murfitt³

et al. 2002

Journal of Endocrinology

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In the pig, nest building occurs in the day preceding parturition (gestation=114-116 days). Nest building behaviour can be induced in pregnant, pseudopregnant and cyclic female pigs following injection of prostaglandin F2 . Here we investigated behaviour and endocrine changes after the administration of indomethacin, which inhibits cyclo-oxygenase enzymes and thus prostaglandin synthesis.In experiment 1, pregnant primiparous pigs (gilts) were blood sampled through jugular vein catheters every 20 min from 1000 h on day 113 of pregnancy and behaviour was recorded until birth. Two hours after pre-partum nest building began, animals received 4 mg/kg indomethacin (n=7) or control vehicle (n=8) intramuscularly. Indomethacin-treated animals showed less nest building than controls between 1 and 5 h after injection (P<0·05), during which time they were mostly inactive and lay down for longer than controls. From 5 h before birth until birth there was no significant treatment difference in nest building behaviour. There was a tendency for the start of birth to be delayed in indomethacin-treated animals. Plasma 13,14-dihydro-15-keto-prostaglandin F2(a major metabolite of prostaglandin F2 ) rose during pre-injection nest building and then fell following indomethacin treatment, but was not significantly different between groups when behaviour differed. Plasma oxytocin, cortisol and progesterone were not significantly affected by treatment. In experiment 2, indomethacintreated non-pregnant gilts (n=7) did not show any changes in activity or posture compared with vehicle-treated controls (n=6) between 90 and 150 min after treatment.These results suggested that indomethacin treatment reversibly and specifically inhibits porcine pre-partum nest building by a mechanism that may involve endogenous prostaglandin F2 synthesis inhibition but is independent of circulating oxytocin, cortisol and progesterone concentrations.

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Oxytocin Secretion and Management of Parturition in the Pig

Cited by 26 publications

References 66 publications

Effectiveness of different farrowing induction protocols in sows using alphaprostol on day 114 of gestation

Effectiveness of different farrowing induction protocols in sows using alphaprostol on day 114 of gestation

Partusinductie bij de zeug

Indomethacin blocks pre-partum nest building behaviour in the pig (Sus scrofa): effects on plasma prostaglandin F metabolite, oxytocin, cortisol and progesterone

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