Oxytocin enhances the perception of biological motion in humans

Kéri, Szabolcs; Benedek, György

doi:10.3758/cabn.9.3.237

Cited by 72 publications

(50 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, consistent with our first hypothesis, a treatment effect was observed in that dogs performed significantly better after oxytocin than saline administration in session 1. This is consistent with findings for humans, demonstrating that oxytocin increases perception of biologically relevant human motion (Kéri and Benedek 2009), which is imperative for social cognitive processing and communication, and supports the notion that oxytocin increases social cognition (see reviews by Bartz et al 2011;Guastella and MacLeod 2012). In addition, when examining difference scores between testing sessions, we observed performance improvements from session 1 to session 2 for point B3 scores in sal-oxy group dogs.…”

Section: Discussionsupporting

confidence: 90%

Oxytocin enhances the appropriate use of human social cues by the domestic dog (Canis familiaris) in an object choice task

et al. 2015

View full text Add to dashboard Cite

It has been postulated that the neuropeptide, oxytocin, is involved in human-dog bonding. This may explain why dogs, compared to wolves, are such good performers on object choice tasks, which test their ability to attend to, and use, human social cues in order to find hidden food treats. The objective of this study was to investigate the effect of intranasal oxytocin administration, which is known to increase social cognition in humans, on domestic dogs' ability to perform such a task. We hypothesised that dogs would perform better on the task after an intranasal treatment of oxytocin. Sixty-two (31 males and 31 females) pet dogs completed the experiment over two different testing sessions, 5-15 days apart. Intranasal oxytocin or a saline control was administered 45 min before each session. All dogs received both treatments in a pseudo-randomised, counterbalanced order. Data were collected as scores out of ten for each of the four blocks of trials in each session. Two blocks of trials were conducted using a momentary distal pointing cue and two using a gazing cue, given by the experimenter. Oxytocin enhanced performance using momentary distal pointing cues, and this enhanced level of performance was maintained over 5-15 days time in the absence of oxytocin. Oxytocin also decreased aversion to gazing cues, in that performance was below chance levels after saline administration but at chance levels after oxytocin administration.

show abstract

Section: Discussionsupporting

confidence: 90%

Oxytocin enhances the appropriate use of human social cues by the domestic dog (Canis familiaris) in an object choice task

et al. 2015

View full text Add to dashboard Cite

show abstract

“…OT appears to affect biological motion detection (Keri and Benedek, 2009), and improves MS as shown in a study by Perry et al (2010), in which a single 24IU dose of intranasal (IN) OT enhanced MS to biological motion in healthy controls (HC). Thus, it appears OT may sharpen the detection of socially relevant stimuli via regulation of the MNS.…”

Section: Introductionmentioning

confidence: 96%

“…The current pilot study, therefore, investigated whether IN OT could enhance MS in response to biological motion in SCZ patients. Since both previously reported studies tested only 24IU-OT, (Keri and Benedek, 2009;Perry et al, 2010), we compared the effects of 24IU-OT and 48IU-OT to explore whether higher doses induce greater MS in HC and SCZ. The study was designed for efficient pilot testing using the National Institutes of Mental Health (NIMH) (http://www.nimh.nih.gov/funding/opportunities-announcements/clinical-trials-foas/index.shtml) guide lines to support "go/no-go" decisions on whether a larger study is justified for rapid translation.…”

Section: Introductionmentioning

confidence: 99%

Effects of intranasal oxytocin on neural processing within a socially relevant neural circuit

Singh

Nunag

Muldoon

et al. 2016

European Neuropsychopharmacology

View full text Add to dashboard Cite

Dysregulation of the Mirror Neuron System (MNS) in schizophrenia (SCZ) may underlie the cognitive and behavioral manifestations of social dysfunction associated with that disorder. In healthy subjects intranasal (IN) oxytocin (OT) improves neural processing in the MNS and is associated with improved social cognition. OT's brain effects can be measured through its modulation of the MNS by suppressing EEG mu-band electrical activity (8-13 Hz) in response to motion perception. Although IN OT's effects on social cognition have been tested in SCZ, OT's impact on the MNS has not been evaluated to date. Therefore, we designed a study to investigate the effects of two different OT doses on biological motion-induced mu suppression in SCZ and healthy subjects. EEG recordings were taken after each subject received a single IN administration of placebo, OT-24IU and OT-48IU in randomized order in a double-blind crossover design. The results provide support for OT's regulation of the MNS in both healthy and SCZ subjects, with the optimal dose dependent on diagnostic group and sex of subject. A statistically significant response was seen in SCZ males only, indicating a heightened sensitivity to those effects, although sex hormone related effects cannot be ruled out. In general, OT appears to have positive effects on neural circuitry that supports social cognition and socially adaptive behaviors. Published by Elsevier B.V. E-mail address: fsingh@ucsd.edu (F. Singh). European Neuropsychopharmacology (]]]]) ], ]]]-]]]Please cite this article as: Singh, F., et al., Effects of intranasal oxytocin on neural processing within a socially relevant neural circuit. European Neuropsychopharmacology (2015), http://dx

show abstract

“…the timing of movement execution) [11]. Similarly, recent studies showed the OT-induced suppression of cortical activity at the alpha/mu and beta bands when biological motion is viewed [12], implying heightened sensitivity towards biological versus non-biological motion [13]. In addition, OT administration modulated social distance between males and females during interactions [14], and mothers' speech stimulated OT release in girls [15].…”

Section: Introductionmentioning

confidence: 88%

Oxytocin shapes parental motion during father–infant interaction

et al. 2013

View full text Add to dashboard Cite

An infant-oriented parental repertoire contributes to an infant's development and well-being. The role of oxytocin (OT) in promoting affiliative bonds and parenting has been established in numerous animal and human studies. Recently, acute administration of OT to a parent was found to enhance the carer's, but at the same time also the infant's, physiological and behavioural readiness for dyadic social engagement. Yet, the exact cues that are involved in this affiliative transmission process remain unclear. The existing literature suggests that motion and vocalization are key social signals for the offspring that facilitates social participation, and that distance and motion perception are modulated by OT in humans. Here, we employed a computational method on video vignettes of human parent-infant interaction including 32 fathers that were administered OT or a placebo in a crossover experimental design. Results indicate that OT modulates parental proximity to the infant, as well as the father's head speed and head acceleration but not the father's vocalization during dyadic interaction. Similarly, the infant's OT reactivity is positively correlated with father's head acceleration. The current findings are the first to report a relationship between the OT system and parental motion characteristics, further suggesting that the cross-generation transmission of parenting in humans might be underlaid by nuanced, infant-oriented, gestures relating to the carer's proximity, speed and acceleration within the dyadic context.

show abstract

Oxytocin enhances the perception of biological motion in humans

Cited by 72 publications

References 34 publications

Oxytocin enhances the appropriate use of human social cues by the domestic dog (Canis familiaris) in an object choice task

Oxytocin enhances the appropriate use of human social cues by the domestic dog (Canis familiaris) in an object choice task

Effects of intranasal oxytocin on neural processing within a socially relevant neural circuit

Oxytocin shapes parental motion during father–infant interaction

Contact Info

Product

Resources

About