Oxytocin but Not Testosterone Modulates Behavioral Patterns in Autism Spectrum Disorders

Lakatošová, Silvia; Nurit, Sheinberg; Pivovarciova, Anna; Husarova, Veronika; Rozenfeld, Irina; Ostatníková, Daniela; Maria, Castejon Ana

doi:10.4236/ojmp.2014.31006

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2017

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“…There are numerous pathways for this association such as alterations in either the brain OT axis, the peptide receptors, and/or in peptide synthesis and processing. Lakatosova et al [2013] 8 children with ASD.…”

Section: Future Directionsmentioning

confidence: 99%

The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper

et al. 2017

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Based on evidence from the relevant research literature, we present a hypothesis that there may be a link between cholesterol, vitamin D, and steroid hormones which subsequently impacts on the development of at least some of the “autisms” [Coleman & Gillberg]. Our hypothesis, driven by the peer reviewed literature, posits that there may be links between cholesterol metabolism, which we will refer to as “steroid metabolism” and findings of steroid abnormalities of various kinds (cortisol, testosterone, estrogens, progesterone, vitamin D) in autism spectrum disorder (ASD). Further research investigating these potential links is warranted to further our understanding of the biological mechanisms underlying ASD. Autism Res 2017. © 2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research. Autism Res 2017, 10: 1022–1044. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

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Section: Future Directionsmentioning

confidence: 99%